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2008 | 2007
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2010 |
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1.
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Isabel Fortier, Paul R Burton,
Paula J Robson, Vincent Ferretti, Julian Little, Francois
L’Heureux, Mylène Deschênes, Bartha M Knoppers, Dany Doiron,
Joost C Keers, Pamela Linksted, Jennifer R Harris, Geneviève
Lachance, Catherine Boileau, Nancy L Pedersen, Carol M
Hamilton, Kristian Hveem, Marilyn J Borugian, Richard P
Gallagher, John McLaughlin, Louise Parker, John D Potter,
John Gallacher, Rudolf Kaaks, Bette Liu, Tim Sprosen, Anne
Vilain, Susan A Atkinson, Andrea Rengifo, Robin Morton,
Andres Metspalu, H Erich Wichmann, Mark Tremblay, Rex L
Chisholm, Andrés Garcia-Montero, Hans Hillege, Jan-Eric
Litton, Lyle J Palmer, Markus Perola, Bruce HR Wolffenbuttel,
Leena Peltonen, and Thomas J Hudson
Quality, quantity and harmony: the DataSHaPER
approach to integrating data across bioclinical studies
IJE Advance Access published on September 2, 2010.
doi:10.1093/ije/dyq139 PDF
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2. |
Jüri Allik,
Anu Realo, René Mõttus,
Tõnu Esko, Janne Pullat and Andres Metspalu
Variance determines self-observer agreement on the
Big Five personality traits
Journal of Research in Personality
Volume 44, Issue 4, August 2010, Pages 421-426
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3. |
Nagirnaja L, Rull K, Uusküla
L, Hallast P, Grigorova M, Laan M (2010) Genomics and
genetics of gonadotropin beta subunit genes: unique FSHB and
duplicated LHB/CGB loci. Mol Cell Endocrinol, May 19. [Epub
ahead of print]; doi: 10.1016/j.mce.2010.04.024
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4. |
Männik J, Vaas P, Rull K,
Teesalu P, Rebane T, Laan M (2010) Differential
Expression Profile of Growth Hormone/Chorionic
Somatomammotropin Genes in Placenta of Small- and
Large-for-Gestational-Age Newborns. J Clin Endocrinol Metab.
95(5):2433-42
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5. |
Kepp K, Org E, Sõber S, Kelgo
P, Viigimaa M, Veldre G, Tõnisson N, Juhanson P,
Putku M, Kindmark A, Kozich V, Laan M (2010)
Hypervariable intronic region in NCX1 is enriched in short
insertion-deletion polymorphisms and showed association with
cardiovascular traits. BMC Med Genet 11:15.
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6. |
Sõber S, Laan M, Annilo T
(2010) MicroRNAs miR-124 and miR-135a are potential
regulators of the mineralocorticoid receptor gene (NR3C2)
expression. Biochem Biophys Res Commun 391(1): 727-32.
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7. |
Grigorova M, Punab M,
Poolamets O, Kelgo P, Ausmees K, Korrovits P,
Vihljajev V, Laan M (2010) Increased Prevalance of
the 211 T Allele of Follicle Stimulating Hormone (FSH)
Subunit Promoter Polymorphism and Lower Serum FSH in
Infertile Men. J Clin Endocrinol Metab 95(1): 100-108.
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8. |
Nikopensius T, Birnbaum S,
Ludwig KU, Jagomägi T, Saag M, Herms S, Knapp M, Hoffmann P,
Nöthen MM, Metspalu A, Mangold E. Susceptibility
locus for nonsyndromic cleft lip with or without cleft
palate on chromosome 10q25 confers risk in Estonian patients.
Eur J Oral Sci 2010; 118: 317-319.
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9. |
Jagomägi T, Nikopensius T,
Krjutškov K, Tammekivi V, Viltrop T, Saag M,
Metspalu A. MTHFR and MSX1 contribute to the risk of
nonsyndromic cleft lip/palate. Eur J Oral Sci 2010; 118:
213-220.
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10. |
Lauris Kaplinski,
Ott Scheler, Sven Parkel,
Priit Palta,
Kadri Toome, Ants Kurg and Maido Remm
Detection
of tmRNA molecules on microarrays at low temperatures using
helper oligonucleotides
BMC Biotechnology
2010, 10:34
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11. |
Sequence
variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
Thorgeir E. Thorgeirsson, Daniel F. Gudbjartsson, Ida
Surakka, Jacqueline M. Vink, Najaf Amin, Frank Geller,
Patrick Sulem, Thorunn Rafnar, Tõnu Esko, Stefan
Walter, Christian Gieger, Rajesh Rawal, Massimo Mangino,
Inga Prokopenko , Reedik Mägi, Kaisu Keskitalo, Iris H.
Gudjonsdottir, Solveig Gretarsdottir, Hreinn Stefansson,
John R. Thompson, Yurii S. Aulchenko, Mari Nelis,
Katja K. Aben, Martin den Heijer, Asger Dirksen, Haseem
Ashraf, Nicole Soranzo, Ana M Valdes, Claire Steves, André G
Uitterlinden, Albert Hofman, Anke Tönjes, Peter Kovacs,
Jouke Jan Hottenga, Gonneke Willemsen, Nicole Vogelzangs,
Angela Döring, Norbert Dahmen, Barbara Nitz, Michele L.
Pergadia, Berta Saez, Veronica De Diego, Victoria Lezcano,
Maria D. Garcia-Prats, Samuli Ripatti, Markus Perola,
Johannes Kettunen, Anna-Liisa Hartikainen, Anneli Pouta,
Jaana Laitinen, Matti Isohanni, Shen Huei-Yi, Maxine Allen,
Maria Krestyaninova, Alistair S Hall, Gregory T. Jones,
Andre M. van Rij, Thomas Mueller, Benjamin Dieplinger,
Meinhard Haltmayer, Steinn Jonsson, Stefan E. Matthiasson,
Hogni Oskarsson, Thorarinn Tyrfingsson, Lambertus A.
Kiemeney, Jose I. Mayordomo, Jes S Lindholt, Jesper Holst
Pedersen, Wilbur A. Franklin, Holly Wolf, Grant W.
Montgomery, Andrew C. Heath, Nicholas G. Martin, Pamela A.F.
Madden, Ina Giegling, Dan Rujescu, Marjo-Riitta Järvelin,
Veikko Salomaa, Michael Stumvoll,Tim D Spector, H-Erich
Wichmann, Andres Metspalu, Nilesh J. Samani, Brenda
W. Penninx, Ben A. Oostra, Dorret I. Boomsma, Henning
Tiemeier, Cornelia M. van Duijn, Jaakko Kaprio, Jeffrey R.
Gulcher, The ENGAGE Consortium, Mark I. McCarthy, Leena
Peltonen , Unnur Thorsteinsdottir1, Kari Stefansson
Nat Genet. 2010
May;42(5):448-53.
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12. |
Braschinsky M,
Rannikmäe K, Tamm R, Metspalu A, Gross-Paju K, Haldre
S.
Hereditaarset spastilist parapleegiat süsteemselt käsitlenud
uuring Eestis tõi esile uusi andmeid.
Eesti Arst, 2010, 89(3), 165 - 170.
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13. |
Tamm R,
Saks K, Pääsuke M. Research on ageing and longevity in
Estonia. Reviews in Clinical Gerontology 2010; 20(3): x - x.
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14. |
Maron E,
Hettema JM, Shlik J.
Advances in molecular genetics of panic disorder.
Mol Psychiatry. 2010 Jan 5.
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15. |
Braschinsky M,
Tamm R, Beetz C, Sachez-Ferrero E, Raukas E, Luus SM,
Gross-Paju K, Boillot C, Canzian F, Metspalu A,
Haldre S
Unique spectrum of SPAST variants in Estonian HSP patients:
presence of benign missense changes but lack of exonic
rearrangements.
BMC
Neurol. 2010 Mar 9;10(1):17.
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16. |
Tamm R.
Novel human pathological mutations. Gene symbol: SPAST.
Disease: Hereditary spastic paraplegia.
Hum Genet. 2010 Jan;127(1):112.
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17. |
Saare M, Lamp M, Kaart T, Karro H,
Kadastik U, Metspalu A, Peters M, Salumets A.
Polymorphisms in MMP-2 and MMP-9 promoter regions are
associated with endometriosis.
Fertil Steril.
2010 Jan 23.
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18. |
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19. |
R. G. Walters, S. Jacquemont, A. Valsesia, A. J. de Smith,
D. Martinet, J. Andersson, M. Falchi, F. Chen, J. Andrieux,
S. Lobbens, B. Delobel, F. Stutzmann, J. S. El-Sayed
Moustafa, J.-C. Chèvre, C. Lecoeur, V. Vatin, S. Bouquillon,
J. L. Buxton, O. Boute, M. Holder-Espinasse, J.-M. Cuisset,
M.-P. Lemaitre, A.-E. Ambresin, A. Brioschi, M. Gaillard, V.
Giusti, F. Fellmann, A. Ferrarini, N. Hadjikhani, D.
Campion, A. Guilmatre, A. Goldenberg, N. Calmels, J.-L.
Mandel, C. Le Caignec, A. David, B. Isidor, M.-P. Cordier,
S. Dupuis-Girod, A. Labalme, D. Sanlaville, M.
Béri-Dexheimer, P. Jonveaux, B. Leheup, K. Õunap, E. G.
Bochukova, E. Henning, J. Keogh, R. J. Ellis, K. D.
MacDermot, M. M. van Haelst, C. Vincent-Delorme, G. Plessis,
R. Touraine, A. Philippe, V. Malan, M. Mathieu-Dramard, J.
Chiesa, B. Blaumeiser, R. F. Kooy, R. Caiazzo, M. Pigeyre,
B. Balkau, R. Sladek, S. Bergmann, V. Mooser, D. Waterworth,
A. Reymond, P. Vollenweider, G. Waeber, A. Kurg, P.
Palta, T. Esko, A. Metspalu, M. Nelis, P. Elliott,
A.-L. Hartikainen, M. I. McCarthy, L. Peltonen, L. Carlsson,
P. Jacobson, L. Sjöström, N. Huang, M. E. Hurles, S.
O’Rahilly, I. S. Farooqi, K. Männik, M.-R. Jarvelin,
F. Pattou, D. Meyre, A. J. Walley, L. J. M. Coin, A. I. F.
Blakemore, P. Froguel & J. S. Beckmann
A new highly
penetrant form of obesity due to deletions on chromosome
16p11.2
Nature.
2010 Feb 4;463(7281):671-5.
PDF
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20. |
Karla V. Allebrandt, Maris Teder-Laving, Mahmut Akyol,
Irene Pichler, Bertram Müller-Myhsok, Peter Pramstaller,
Martha Merrow, Thomas Meitinger, Andreas Metspalu,
and Till Roenneberg
CLOCK Gene
Variants Associate with Sleep Duration in Two Independent
Populations
BIOL PSYCHIATRY 2010;xx:xxx,
doi:10.1016/j.biopsych.2009.12.026,
PDF
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21. |
Patrick T Ellinor, Kathryn L Lunetta, Nicole L Glazer, Arne
Pfeufer, Alvaro Alonso,
Mina K Chung, Moritz F Sinner, Paul I W de Bakker, Martina
Mueller, Steven A Lubitz, Ervin Fox, Dawood Darbar, Nicholas
L Smith, Jonathan D Smith, Renate B Schnabel, Elsayed Z
Soliman, Kenneth M Rice, David R Van Wagoner, Britt-M
Beckmann, Charlotte van Noord, Ke Wang, Georg B Ehret,
Jerome I Rotter, Stanley L Hazen, Gerhard Steinbeck, Albert
V Smith, Lenore J Launer, Tamara B Harris, Seiko Makino,
Mari Nelis, David J Milan, Siegfried Perz, Tõnu Esko,
Anna Köttgen, Susanne Moebus, Christopher Newton-Cheh, Man
Li, Stefan Möhlenkamp, Thomas J Wang, W H Linda Kao,
Ramachandran S Vasan, Markus M Nöthen, Calum A MacRae, Bruno
H Ch Stricker, Albert Hofman, André G Uitterlinden, Daniel
Levy, Eric Boerwinkle, Andres Metspalu, Eric J Topol,
Aravinda Chakravarti, Vilmundur Gudnason, Bruce M Psaty, Dan
M Roden, Thomas Meitinger, H-Erich Wichmann, Jacqueline C M
Witteman, John Barnard, Dan E Arking, Emelia J Benjamin,
Susan R Heckbert & Stefan Kääb
Common variants
in KCNN3 are associated with lone atrial fibrillation
Nat Genet. 2010 Mar;42(3):240-4,
PDF
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2009
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1.
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Viltrop T, Krjutškov K, Palta P, Metspalu A.
Comparison of DNA extraction methods for
multiplex PCR.
Anal Biochem. 2010 Mar 15;398(2):260-2.
PDF
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2.
|
Theodoraki EV, Nikopensius T, Suhorutšenko J, Papamikos V,
Kolovou GD,
Peppes V, Panagiotakos D, Limberi S, Zakopoulos N, Metspalu A,
Dedoussis GV.
ROS1 Asp2213Asn
polymorphism is not associated with coronary artery
disease in a Greek case-control study.
Clin Chem Lab Med. 2009 Oct 28.
|
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3.
|
Nikopensius T, Ambrozaitytė L,
Ludwig KU, Birnbaum S, Jagomägi T, Saag M, Matulevičienė A,
Linkevičienė L, Herms S, Knapp M, Hoffmann P, Nöthen MM, Kučinskas
V, Metspalu A, Mangold E.
Replication of novel susceptibility locus for nonsyndromic cleft lip
with or without cleft palate on chromosome 8q24 in Estonian and
Lithuanian patients.
Am J Med Genet A. 2009
Oct 16;149A(11):2551-2553.
PDF
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4.
|
M. Kuningas, L. May,
R. Tamm, D. van Bodegom, A H.J. van den Biggelaar,
J. J. Meij, M. Frölich, J. B. Ziem, H. E.D. Suchiman, A.
Metspalu, E. P. Slagboom and R. G.J. Westendorp.
Selection for Genetic Variation Inducing Pro-Inflammatory Responses
under Adverse Environmental Conditions in a Ghanaian Population.
PlosOne, 2009. PDF
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5.
|
Maria Teresa Landi, Nilanjan
Chatterjee, Kai Yu, Lynn R. Goldin, Alisa M. Goldstein,
Melissa Rotunno, Lisa Mirabello, Kevin Jacobs, William
Wheeler, Meredith Yeager,
Andrew W. Bergen, Qizhai Li, Dario Consonni, Angela C.
Pesatori, Sholom Wacholder, Michael Thun, Ryan Diver, Martin
Oken, Jarmo Virtamo, Demetrius Albanes, Zhaoming Wang,
Laurie Burdette, Kimberly F. Doheny, Elizabeth W. Pugh,
Cathy Laurie, Paul Brennan, Rayjean Hung, Valerie Gaborieau,
James D. McKay, Mark Lathrop, John McLaughlin, Ying Wang,
Ming-Sound Tsao, Margaret R. Spitz, Yufei Wang, Hans Krokan,
Lars Vatten, Frank Skorpen, Egil Arnesen, Simone Benhamou,
Christine Bouchard, Andres Metsapalu, Tonu Vooder, Mari
Nelis, Kristian Välk, John K. Field, Chu Chen, Gary
Goodman, Patrick Sulem, Gudmar Thorleifsson, Thorunn Rafnar,
Timothy Eisen, Wiebke Sauter, Albert Rosenberger, Heike
Bickebo¨ller, Angela Risch, Jenny Chang-Claude, H. Erich
Wichmann, Kari Stefansson, Richard Houlston,16 Christopher
I. Amos, Joseph F. Fraumeni Jr., Sharon A. Savage, Pier
Alberto Bertazzi, Margaret A. Tucker, Stephen Chanock, and
Neil E. Caporaso
A Genome-wide Association Study of Lung Cancer Identifies a
Region of Chromosome 5p15 Associated with Risk for
Adenocarcinoma
The American Journal of Human Genetics 85, 1–13, November
13, 2009 PDF
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6.
|
Soh J, Okumura N, Lockwood WW, Yamamoto H,
Shigematsu H, Zhang W, Chari R, Shames DS, Tang X, Macaulay
C, Varella-Garcia M, Vooder T, Wistuba II, Lam S,
Brekken R, Toyooka S, Minna JD, Lam WL, Gazdar AF.
Oncogene Mutations, Copy Number
Gains and Mutant Allele Specific Imbalance (MASI) Frequently
Occur Together in Tumor Cells.
PLoS One.
2009 Oct 14;4(10):e7464.
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7.
|
Lips EH,
Gaborieau V, McKay JD, Chabrier A, Hung RJ, Boffetta P,
Hashibe M, Zaridze D, Szeszenia-Dabrowska N, Lissowska J,
Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout
V, Field JK, Liloglou T, Xinarianos G, McLaughlin J, Liu G,
Skorpen F, Elvestad MB, Hveem K, Vatten L, Study E, Benhamou
S, Lagiou P, Holc?tov? I, Merletti F, Kjaerheim K, Agudo A,
Castellsagué X, Macfarlane TV, Barzan L, Canova C, Lowry R,
Conway DI, Znaor A, Healy C, Curado MP, Koifman S, Eluf-Neto
J, Matos E, Menezes A, Fernandez L, Metspalu A, Heath
S, Lathrop M, Brennan P.
Association between a 15q25 gene variant, smoking quantity
and tobacco-related cancers among 17 000 individuals.
Int J Epidemiol. 2009 Sep 23.
|
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8.
|
Annilo T,
Kepp K, Laan M. Natural antisense transcript of
natriuretic peptide precursor A (NPPA): structural
organization and modulation of NPPA expression.
BMC Mol Biol. 2009 Aug 11;10:81. PDF
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9.
|
Sõber
S, Org E, Kepp K, Juhanson P, Eyheramendy S, Gieger C,
Lichtner P, Klopp N, Veldre G, Viigimaa M, Döring A,
Putku M, Kelgo P, Shaw-Hawkins
S, Howard P, Onipinla A, Dobson RJ, Newhouse SJ, Brown M,
Dominiczak A, Connell J, Samani N, Farrall M, Caulfield
M, Munroe PB, Illig T, Wichmann HE, Meitinger T, Laan M
(2009) Targeting 160 candidate genes for blood pressure
regulation with a genome-wide genotyping array. PLoS ONE
4(6): e6034, p. 1-13; doi:10.1371/journal.pone.0006034
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10.
|
Hallast P, Laan M (2009)
Evolution of the chorionic gonadotropin beta genes in
primates. In: Encyclopedia of Life Science (ELS),
John Wiley & Sons, Ltd: Chichester. p. 1-12; DOI:
10.1002/9780470015902.a0021966
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11.
|
Org E, Eyheramendy S, Juhanson
P, Gieger C, Lichtner P, Klopp N, Veldre G, Döring
A, Viigimaa M, Sõber S, Tomberg K, Eckstein
G, KORA, Kelgo P, Rebane T, Shaw-Hawkins
S, Howard P, Onipinla A, Dobson RJ, Newhouse SJ, Brown M,
Dominiczak A, Connell J, Samani N, Farrall M, BRIGHT, Caulfield
M, Munroe PB, Illig T, Wichmann HE, Meitinger T, Laan M
(2009) Genome-wide scan identifies CDH13 as a novel
susceptibility locus contributing to blood pressure
determination in two European populations. Hum Mol Genet
18: 2288-2296; doi:10.1093/hmg/ddp198
|
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12,
|
Newton-Cheh C, Johnson T, Gateva
V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC,
Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F,
Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT,
Nilsson P, van der Harst P, Polidoro S, Grobbee DE,
Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A,
Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL;
Wellcome Trust Case Control Consortium, Brown M, Dominiczak
A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS,
Bergmann S, Lim N, Song K, Vollenweider P, Waeber G,
Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A,
Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V,
Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN,
Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle
LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle
TT, Willer CJ, Bergman RN, Morken MA, Döring A, Gieger C,
Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE,
Kathiresan S, Marrugat J, O'Donnell CJ
, Schwartz SM, Siscovick DS, Subirana I, Freimer NB,
Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta
A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A,
Hamsten A, Peden JF, Seedorf U, Syvänen AC, Tognoni G,
Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, Dörr
M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T,
Rettig R, Völker U, Galan P, Gut IG, Hercberg S, Lathrop GM,
Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G,
Salomaa V, Laakso M, Elosua R, Forouhi NG, Völzke H,
Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis
G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli
S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J,
Altshuler D, Strachan DP, Laan M, Meneton P, Wareham
NJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ,
Elliott P, Abecasis GR, Caulfield M, Munroe PB (2009) Eight
blood pressure loci identified by genomewide association
study of 34,433 people of European ancestry.
Nature Genet 41: 666 – 676; DOI:
10.1038/ng.384
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13.
|
Newhouse
S, Farrall M, Wallace C, Hoti M, Burke B, Howard P, Onipinla
A, Lee K, Shaw-Hawkins S, Dobson R, Brown M, Samani N,
Dominiczak A, Connell JM, Webster J, Lathrop GM, Kooner J,
Clarke R, Collins R, Laan M, Org E, Juhanson P, Veldre G,
Viigimaa M, Eyheramendy S, Cappuccio FP, Ji C, Iacone R,
Strazzullo P, Kumari M, Marmot M, Brunner E, Caulfield M,
Munroe PB (2009) Polymorphisms in the WNK1 gene are
associated with blood pressure variation and urinary
potassium excretion. PLoS ONE 4(4): e5003, p.
1-14; doi:10.1371/journal.pone.0005003
|
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14.
|
Ott Scheler, Barry Glynn, Sven Parkel, Priit
Palta, Kadri Toome, Lauris Kaplinski, Maido Remm,
Majella Maher and Ants Kurg
Fluorescent labeling of NASBA
amplified tmRNA molecules for microarray applications
BMC Biotechnology 2009, 9:45doi:10.1186/1472-6750-9-45,
PDF
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15.
|
Mari Nelis, Tõnu Esko, Reedik Mägi, Fritz Zimprich, Alexander
Zimprich, Draga Toncheva, Sena Karachanak, Tereza
Piskáčková, Ivan Balaščák,
Leena Peltonen, Eveliina Jakkula, Karola
Rehnström, Mark Lathrop, Simon Heath, Pilar
Galan, Stefan Schreiber, Thomas Meitinger, Arne Pfeufer,
H-Erich Wichmann, Béla Melegh, Noémi Polgár, Daniela Toniolo, Paolo
Gasparini, Pio D'Adamo, Janis Klovins, Liene Nikitina-Zake, Vaidutis
Kučinskas, Jūratė Kasnauskienė, Jan Lubinski,
Tadeusz Debniak, Svetlana Limborska, Andrey Khrunin, Xavier Estivill, Raquel
Rabionet, Sara Marsal, Antonio Julià,
Stylianos E. Antonarakis, Samuel Deutsch, Christelle
Borel, Homa Attar, Maryline
Gagnebin, Milan Macek, Michael Krawczak, Maido Remm, Andres
Metspalu
Genetic Structure of Europeans: a view from the North-East
PlosOne 2009, http://dx.plos.org/10.1371/journal.pone.0005472
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16. |
Maron E, Tammiste
A, Kallassalu K, Eller T, Vasar V, Nutt DJ, Metspalu
A.
Serotonin
transporter promoter region polymorphisms do not influence
treatment response to escitalopram in patients with major
depression.
Eur
Neuropsychopharmacol. 2009 Jun;19(6):451-6. PDF
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17. |
B W M van
Bon,
H C Mefford, B Menten, D A Koolen,
A J Sharp, W M Nillesen, J W Innis,
T J L de Ravel, C L Mercer, M Fichera,
H Stewart, L E Connell, K Ounap,
B Castle, N Van der Aa, C van
Ravenswaaij, M A Nobrega, C Serra-Juhé,
I Simonic, N de Leeuw, R Pfundt,
E M Bongers, C Baker, P Finnemore,
S Huang, V K Maloney, J A Crolla,
M van Kalmthout, M Elia, G Vandeweyer,
J P Fryns, S Janssens, N Foulds,
S Reitano, K Smith, S Parkel,
B Loeys, C G Woods, A
Oostra, F Speleman, A C C Pereira, A
Kurg, Lionel Willatt, S J L Knight,
J R Vermeesch, C Romano, J C Barber,
G Mortier, L A Perez-Jurado, F Kooy,
H G Brunner, E E Eichler, T
Kleefstra and B B A de Vries
Further delineation of the 15q13 microdeletion and duplication
syndromes: A clinical spectrum varying from non-pathogenic to a severe
outcome,
J Med Genet. Published Online First: 15 April 2009.
doi:10.1136/jmg.2008.063412, PDF
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18. |
Puusepp
H, Zilina O, Teek R, Männik K, Parkel S, Kruustük
K, Kuuse K, Kurg A, Ounap K. 5.9 "Mb
microdeletion in chromosome band 17q22-q23.2 associated with
tracheo-esophageal fistula and conductive hearing
loss."
Eur J Med Genet. 2009 Jan-Feb;52(1):71-4. PDF
|
|
19. |
Van der
Aa N, Rooms L, Vandeweyer G, van den Ende J, Reyniers E,
Fichera M, Romano C, Delle Chiaie B, Mortier G, Menten B,
Destrée A, Maystadt I, Männik K, Kurg A,
Reimand T, McMullan D, Oley C, Brueton L, Bongers EM, Bregje
W Bon MV, Pfund R, Jacquemont S, Ferrarini A, Martinet D,
Schrander-Stumpel C, Stegmann AP, Frints SG, de Vries BB,
Ceulemans B, Kooy RF. "Fourteen new cases contribute to
the characterization of the 7q11.23
microduplication syndrome." Eur J Med Genet. 2009 Feb
26. PDF
|
|
20. |
Khrunin
A, Mihailov E, Nikopensius T, Krjutškov K, Limborska
S, Metspalu A.
Analysis of Allele and Haplotype Diversity Across 25 Genomic
Regions in Three Eastern European Populations.
Hum Hered 2009;68:35-44 (DOI: 10.1159/000210447)
|
|
21. |
Cristina
Canova, Mia Hashibe, Lorenzo
Simonato, Mari Nelis, Andres
Metspalu, Pagona Lagiou, Dimitrios
Trichopoulos, Wolfgang Ahrens, Iris
Pigeot, Franco Merletti, Lorenzo
Richiardi, Renato Talamini, Luigi
Barzan, Gary J. Macfarlane, Tatiana
V. Macfarlane, Ivana Holcátová, Vladimir
Bencko, Simone Benhamou, Christine
Bouchardy, Kristina Kjaerheim, Ray
Lowry, Antonio Agudo, Xavier
Castellsagué, David I. Conway, Patricia
A. McKinney, Ariana Znaor, Bernard
E. McCartan, Claire M. Healy, Manuela
Marron and Paul Brennan
Genetic
Associations of 115 Polymorphisms with Cancers of the Upper
Aerodigestive Tract across 10 European Countries: The ARCAGE
Project
Cancer Research 69, 2956, April 1, 2009, 2956-2965
|
|
22. |
Kaarel Krjutškov, Triin
Viltrop, Priit Palta, Ene Metspalu, Erika Tamm, Siim
Suvi, Katrin Sak, Alo Merilo, Helena Sork, Rita Teek, Tiit
Nikopensius, Toomas Kivisild and Andres Metspalu
Evaluation of the
124-plex SNP typing microarray for forensic testing
Forensic Sci Int Genet.
2009 Dec;4(1):43-8.
PDF
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2008
|
|
|
1. |
Helen
Puusepp, Tiina Kahre, Hiljar Sibul, Viljo Soo,
Ilona Lind, Elve Raukas and Katrin Õunap.
Prevalence of the Fragile X Syndrome Among Estonian Mentally
Retarded and the Entire Children’s Population
J Child Neurol 2008; 23; 1400-1405 PDF
|
|
2.
|
Männik
J. et
al (2008) Expression
pattern of human Growth Hormone Chorionic Somatomammotropin
(hGH/CSH) gene cluster in normal and complicated pregnancies.
Placenta 29 (8), A43.
|
|
3. |
Veldre
G.
et al (2008) HYPEST,
first hypertension targeted sample collection in Estonian
population. J Hypertens
26, 107.
|
|
4. |
Rull
K.
et al (2008)
Expressional profile and genetic
variation of chorionic gonadotropin beta genes is associated
to recurrent miscarriages.
Placenta
29 (8), A46.
|
|
5. |
Teek
R, Oitmaa
E, Kruustük
K, Zordania
R, Joost
K, Raukas
E, Tõnisson
N, Gardner
P, Schrijver
I, Kull
M, Ounap
K.
Splice variant IVS2-2A>G in the SLC26A5 (Prestin) gene in
five Estonian families with hearing loss.
Int
J Pediatr Otorhinolaryngol. 2009 Jan;73(1):103-7.
Epub 2008 Nov 22.
|
|
6. |
Lagiou P, Georgila C, Minaki P,
Ahrens W, Pohlabeln H, Benhamou S, Bouchardy
C, Slamova A, Schejbalova M, Merletti F, Richiardi L,
Kjaerheim K, Agudo A,
Castellsague X, Macfarlane TV, Macfarlane GJ, Talamini R,
Barzan L, Canova
C, Simonato L, Lowry R, Conway DI, McKinney PA, Znaor A,
McCartan BE, Healy
C, Nelis M, Metspalu A, Marron M, Hashibe M, Brennan
PJ.
Alcohol-related cancers and genetic susceptibility in Europe:
the ARCAGE
project: study samples and data collection.Eur J Cancer Prev.
2008 Sep 30. [Epub ahead of print]
PMID: 18830131 [PubMed - as supplied by publisher]
|
|
7. |
Knapp, DC., Keller, A.,
D'Onofrio, J., Lubys, A., Serva, S., Kurg, A.,
Remm, M., Kwiatkowski, M, and Engels, JW. (2008) Synthesis
of four
colors fluorescently labelled 3'-O-blocked nucleotides with
fluoride
cleavable blocking group and linker for array based
Sequencing-by-Synthesis applications. /Nucleic Acids Symp
Ser/ (Oxf).
(52):345-6.
|
|
8. |
Saare M, Belousova A,
Punab M, Peters M, Haller K, Ausmees K, Poolamets O,
Karro H, Metspalu A, Salumets A.
Androgen receptor gene haplotype is associated with male
infertility.Int J Androl. 2008 Aug;31(4):395-402.
PMID: 17651405 [PubMed - indexed for MEDLINE]
|
|
9. |
Maron E, Kallassalu K,
Tammiste A, Kolde R, Vilo J, Tõru I, Vasar V, Shlik
J, Metspalu A.
Peripheral gene expression profiling of CCK-4-induced panic
in healthy
subjects.Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 2.
[Epub ahead of print]
PMID: 19051287 [PubMed - as supplied by publisher] PDF
|
|
10. |
Signe
Altmae, Kadri Haller, Maire Peters, Merli
Saare, Outi Hovatta, Anneli Stavreus-Evers, Agne Velthut,
Helle Karro, Andres Metspalu, Andres Salumets,
Aromatase gene (CYP19A1) allele
variants are essential to controlled ovarian
hyperstimulation outcome
RBMOnline, Volume 17, No 3,
September 2008
|
|
11. |
Sedman,
L.;
Padhukasahasram, B.; Kelgo, P.; Laan, M. (2008). Complex Signatures of Locus-Specific
Selective Pressures and Gene Conversion on Human Growth
Hormone/Chorionic Somatomammotropin Genes. Hum
Mutat, 29, 1181 - 1193.
|
|
12. |
Grigorova,
M.;
Punab, M.; Ausmees, K.; Laan, M. (2008). FSHB promoter polymorphism within evolutionary
conserved element is associated with serum FSH level in men.
Hum Reprod, 23,
2160 - 2166. PDF
|
|
13. |
Hallast,
P.;
Saarela, J.; Palotie, A.; Laan, M. (2008). High divergence in primate-specific duplicated
regions: Human and chimpanzee Chorionic Gonadotropin Beta
genes. BMC Evol Biol,
8, 1 - 14. PDF
|
|
14. |
Juhanson,
P.; Kepp, K.; Org, E.; Veldre, G.; Kelgo, P.;
Rosenberg, M.; Viigimaa, M.; Laan,
M. (2008). N-acetyltransferase 8, a positional candidate
for blood pressure and renal regulation: resequencing,
association and in silico study. BMC
Med Genet, 9, 1 - 12,
PDF
|
|
15. |
Pullat, J., Kusnezow, W., Jaakson, K., Beier, M.,
Hoheisel, J.D.,
Metspalu, A.,
Arrayed Primer Extension on
in situ
Synthesized 5'→3'
Oligonucleotides in Microchannels
New Biotechnology
(2008), August 14, PMID:
18786662
|
|
16. |
Riin Tamm,
Kersti Oselin, Kristi Kallassalu,
Reedik Mägi, Kaili Anier, Maido Remm,
Andres Metspalu
Thiopurine
S-methyltransferase (TPMT) pharmacogenetics: three new
mutations and haplotype analysis in the Estonian population
Clin Chem
Lab Med 2008;46(7):974-979
|
|
17. |
Pullat J, Metspalu A. Arrayed primer extension
reaction for genotyping on oligonucleotide microarray.
Methods Mol Biol. 2008;444:161-7 PDF
|
|
18. |
Kousoulidou,
L.; Männik, K.; Zilina, O.; Parkel, S.; Palta, P.;
Remm, M.; Kurg, A.; Patsalis, P.C. (2008).
Application of two different microarray-based copy-number
detection methodologies - array-comparative genomic
hybridization and array-multiplex amplifiable probe
hybridization - with identical amplifiable target sequences.
Clinical Chemistry and Laboratory Medicine, 46, 722 - 724.
|
|
19. |
Kaarel Krjutškov,
Reidar Andreson, Reedik Mägi, Tiit
Nikopensius, Andrey Khrunin, Evelin Mihailov,
Veronika Tammekivi, Helena Sork, Maido Remm and
Andres Metspalu
Development of a single tube 640-plex genotyping method for
detection of nucleic acid variations on microarrays
Nucleic Acids Res. 2008
Jul;36(12):e75. Epub 2008 Jun 5.
PDF
|
|
20. |
Kousoulidou L,
Männik K, Sismani C, Zilina O, Parkel S, Puusepp H,
Tõnisson N,Palta P, Remm M, Kurg A, Patsalis PC. Array-MAPH: a
methodology for the detection of locus copy-number changes in
complex genomes. Nat Protoc. 2008;3(5):849-65.
|
|
21. |
Haller
K, Salumets A, Uibo R.
Anti-FSH antibodies associate with poor outcome of ovarian
stimulation in IVF.
Reprod Biomed Online. 2008;16(3):350-355.
PDF
|
|
22. |
Rull,
K.; Nagirnaja, L.;
Ulander, V.-M.; Kelgo,
P.; Margus, T.; Kaare,
M.; Aittomäki, K.; Laan,
M. (2008). Chorionic Gonadotropin Beta gene variants are
associated with recurrent miscarriage in two European
populations. J Clin
Endocrinol Metab, 93(12): 4697-4706.
|
|
23. |
Rull,
K.; Hallast, P.; Uusküla, L.;
Jackson, J.; Punab, M.; Salumets, A.; Campbell, R.; Laan,
M. (2008). Fine scale quantification of HCG beta gene
transcription in human trophoblastic and nonmalignant
non-trophoblastic tissues. Mol
Hum Reprod, 14, 23 - 31.PDF
|
|
24. |
Caulfield,
M.J.; Munroe, P.B.; O'Neill, D.; Witkowska, K.; Charchar,
F.; Doblado, M.; Evans, S.; Eyheramendy, S.; Onipinia, A.;
Howard, P.; Shaw-Hawkins, S.; Dobson, R.J.; Wallace, C.;
Newhouse, S.J.; Brown, M.; Connell, J.M.; Dominiczak, A.;
Farrall, M.; Lathrop, G.M.; Samani, N.; Kumari, M.; Marmot,
M.; Brunner, E.; Chambers, J.; Elliott, P.; Kooner, J.; Laan,
M.; Org, E.; Veldre, G.; Viigimaa, M.; Cappuccio, F.P.;
Ji, C.; Iacone, R.; Strazzullo, P. ; Moley, K.H.; Cheeseman,
C. (2008). SLC2A9 Is a High-Capacity Urate Transporter in
Humans. PLOS Med,
5, 0001 - 0015.
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2007
|
|
|
1.
|
Haller K, Sikut A, Karro H, Uibo
R, Salumets A.
Circulating anti-follicle-stimulating hormone immunoglobulin
A in women: a sperm-prone reaction of mucosal tolerance?
Fertility and Sterility. 2007 Dec 21;
PDF
|
|
2.
|
Kousoulidou L, Parkel S,
Zilina O, Palta P, Puusepp H, Remm M, Turner G, Boyle J,
van Bokhoven H, de Brouwer A, Van Esch H, Froyen G, Ropers
HH, Chelly J, Moraine C, Gecz J, Kurg A, Patsalis PC.
Screening of 20 patients with X-linked mental retardation
using chromosome X-specific array-MAPH.
Eur J Med Genet. 50(2007)399e410,
PDF
|
|
3.
|
Kepp K, Juhanson P, Kozich V,
Ots M, Viigimaa M, Laan M.:Resequencing PNMT in European
hypertensive and normotensive individuals: no common
susceptibilily variants for hypertension and purifying
selection on intron 1. BMC Med Genet. 2007 Jul 23;8:47.
PDF
|
|
4.
|
Pullat, Janne; Metspalu,
Andres. Arrayed primer extension reaction for genotyping
on oligonucleotide microarray. In Methods in Molecular
Biology: Prenatal Diagnosis: Preface. Ed by S. Hahn, L.G.
Jackson. Prenatal Diagnosis (435), Series: Methods in
Molecular Biology , Vol. 444 ISBN: 978-1-58829-803-4. Humana
Press [in Press]
|
|
5.
|
Roovere T, Peters M,
Horelli-Kuitunen N, Molter-Vaar T, Punab M, Rootsi S,
Poolamets O, Salumets A. Cytogenetic and molecular
characterization of the derivative Y chromosome: a case
study of an azoospermic patient. Clin Genet. 2007
Nov;72(5):460-3 PDF
|
|
6.
|
Saare M, Belousova A, Punab M,
Peters M, Haller K, Ausmees K, Poolamets O, Karro H,
Metspalu A, Salumets A. Androgen receptor gene
haplotype is associated with male infertility. Int J Androl.
2007 Jul 25; [Epub ahead of print].
PDF
|
|
7.
|
Pullat J, Fleisher R, Becker N, Beier
M, Metspalu A, Hoheisel JD.
Optimization of candidate-gene SNP-genotyping
by flexible oligonucleotide microarrays; analyzing
variations in immune regulator genes of hay-fever samples.
BMC Genomics
2007 Aug
17, 8:282 PDF
|
|
8.
|
Magi R, Pfeufer A, Nelis M, Montpetit A, Metspalu
A, Remm M.
Evaluating the performance of commercial whole-genome marker
sets for capturing common genetic variation.
BMC
Genomics. 2007 Jun 11;8:159.
|
|
9.
|
Merisalu A, Punab M,
Altmae S, Haller K, Tiido T, Peters M,
Salumets A. The contribution of genetic variations of
aryl hydrocarbon receptor pathway genes to male factor
infertility. Fertil Steril. 2007 Jun 6; [Epub ahead of print]
PDF
|
|
10.
|
Altmae, S., Haller, K., Peters, M., Hovatta, O., Stavreus-Evers, A., Karro,
H., Metspalu, A., Salumets, A.
Allelic estrogen receptor 1 (ESR1) gene
variants predict the outcome of ovarian stimulation in in
vitro fertilization. Molecular Human Reproduction, May
30, 2007. pdf
|
|
11. |
Haller, K., Laisk, T., Peters,
M., Talving, E., Karits, P., Karro, H., Uibo, R.,
Salumets, A. (2007) VNTR I/I genotype of insulin gene is
associated with the increase of follicle number independent
from polycystic ovary syndrome.
Acta Obstetricia et Gynecologica Scandinavica, 86(6):726-32.
|
|
12. |
Merisalu,
A., Punab M., Altmäe,
S., Haller, K., Tiido. T., Peters,
M., Salumets,
A. The
contribution of genetic variations of aryl hydrocarbon
receptor pathway genes to male infertility. Fertility and
Sterility, in press.
|
|
13. |
Saare, M., Belousova,
A., Punab,
M., Peters,
M.,
Haller, K., Ausmees, K., Poolamets, O., Karro, H., Metspalu,
A., Salumets,
A.
Androgen receptor gene haplotype is associated with male
infertility. International Journal of Andrology, in
press.
|
|
14. |
Haller
K, Salumets A, Grigorova M, Talja I, Salur L, Bene
MC, Laan M, Uibo R.
Putative predictors of antibodies against
follicle-stimulating hormone in female infertility: a study
based on in vitro fertilization patients.
Am
J Reprod Immunol. 2007 Mar;57(3):193-200.
|
|
15. |
International
patent application #PCT/EE2007/000003,
A
method to determine single nucleotide polymorphisms and mutations in
nucleic acid sequence.
Priority Date: 06.03.2007
Inventors: Kaarel Krjutškov, Andres Metspalu
|
|
16. |
J.Schliwka,
J. Pullat, E.-M. Devilliers, J.D. Hoheisel, M. Beier
Mit der Geniom-Microarray-Technologie HPV-Genotypen auf der
Spur
Biospectrum, vol. 1, February 2007, 13. Jahrgang, pp.
52-53. PDF
|
|
17. |
Patsalis
PC, Kousoulidou L, Mannik K, Sismani C, Zilina O,
Parkel S, Puusepp H, Tonisson N, Palta P, Remm M, Kurg
A.
Detection of small genomic imbalances using microarray-based
multiplex amplifiable probe hybridization.
Eur
J Hum Genet. 2007 Feb;15(2):162-72. Epub 2006 Nov 22.
|
|
18. |
Grigorova
M, Rull K, Laan M.
Haplotype structure of FSHB, the beta-subunit gene for
fertility-associated follicle-stimulating hormone: possible
influence of balancing selection.
Ann Hum Genet.
2007 Jan;71(Pt 1):18-28.
|
|
19. |
Hallast
P, Rull K, Laan M.
The evolution and genomic landscape of CGB1 and CGB2 genes.
Mol Cell
Endocrinol. 2007 Jan 2;260-262:2-11. Epub 2006 Oct
19.
|
|
20. |
Eesti kasulik mudel
“Päriliku
vähiriski analüüsimeetod”.
Taotluse number on U200700047, taotleja: Eesti Biokeskus,
leiutajad: Andres Metspalu, Toomas Veidebaum,
Kristiina Tamboom, Helena Sork, Krista Kaasik,
Neeme Tõnisson ja Ants Kurg.
|
|
21. |
Rahvusvaheline (PCT) patendi taotlus
"A
method to determine single nucleotide polymorphisms and mutations in
nucleic acid sequence.
Taotluse
number: PCT/EE2007/000003.
Taotleja:
Eesti Biokeskus
Leiutajad:
Kaarel Krjutškov, Andres Metspalu
|
|
|
|
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2006
|
|
|
1.
|
US
patent application #US11/584934, Method and Apparatus
for Detection and Analysis of Biological Materials through Laser
Induced Fluorescence.
Priority date: 23.10.2006
Inventors: Jevgeni Berik, Ants Kurg, Andres Metspalu
|
|
2.
|
Kõks, S., Nikopensius,
T., Koido, K., Maron, E., Altmäe,
S., Heinaste, E., Vabrit, K., Tammekivi,
V., Hallast, P., Kurg, A., Shlik, J., Vasar, V., Metspalu,
A., Vasar, E. (2006) Analysis of SNP profiles in patients with
major depressive disorder.
Int. J.
Neuropsychopharmacol. 9 (2): 167-174.
|
|
3.
|
Annilo
T,
Chen ZQ, Shulenin S, Costantino J, Thomas L, Lou H, Stefanov S, Dean M.
Evolution of the vertebrate ABC gene family: analysis of gene birth
and death.
Genomics. 2006 Jul;88(1):1-11.
|
|
4.
|
Patsalis PC, Kousoulidou L, Mannik K,
Sismani C, Zilina O, Parkel S, Puusepp H, Tonisson N,
Palta P, Remm M, Kurg A.
Detection of small genomic imbalances using microarray-based multiplex
amplifiable probe hybridization.
Eur
J Hum Genet. 2006 Nov 22
|
|
5.
|
Haller K, Sarapik A, Talja
I, Salumets A, Uibo R. "Controlled ovarian
hyperstimulation changes the prevalence of serum autoantibodies in in
vitro fertilization patients".
Am J Reprod Immunol. 2006 Nov;56(5-6):364-70. PDF
|
|
6.
|
Saal, K; Tätte, T; Tulp, I; Kink,
I; Kurg, A; Mäeorg, U; Rinken, A;
Lõhmus, A (2006). Sol-gel films for DNA microarray applications.
Materials Letters, 60(15), 1833 - 1838. PDF
|
|
7.
|
Oiglane-Shlik E, Talvik T, Zordania R,
Poder H, Kahre T, Raukas E, Ilus T, Tasa G, Bartsch O, Vaisanen
ML, Ounap K.
Prevalence of Angelman syndrome and Prader-Willi syndrome in Estonian
children: sister syndromes not equally represented.
Am J Med
Genet A. 2006 Sep 15;140(18):1936-43. PDF
|
|
8.
|
Gardner P, Oitmaa E, Messner A,
Hoefsloot L, Metspalu A, Schrijver I.
Simultaneous multigene mutation detection in patients with
sensorineural hearing loss through a novel diagnostic microarray: a
new approach for newborn screening follow-up.
Pediatrics. 2006 Sep;118(3):985-94.
PDF
|
|
9.
|
Alexandre Montpetit,
Mari Nelis, Philippe Laflamme, Reedik Magi, Xiayi Ke, Maido
Remm, Lon Cardon, Thomas J Hudson, and Andres Metspalu
An Evaluation of the Performance of Tag SNPs Derived from HapMap in a
Caucasian Population.
PLoS Genet. 2006 Mar 10;2(3):e27 Full
article
|
|
10.
|
Andres Salumets, Anne-Maria
Suikkari, Sirpa Mäkinen, Helle Karro, Anu Roos ja Timo Tuuri
“Frozen embryo transfers: implications of clinical and embryological
factors on the pregnancy outcome”
Human Reproduction 2006 21(9): 2368-2374;
|
|
11.
|
Shadrina
M, Nikopensius T, Slominsky P, Illarioshkin S,
Bagyeva G, Markova E, Ivanova-Smolenskaia I, Kurg A,
Limborska S, Metspalu A.
Association study of sporadic Parkinson's disease genetic
risk factors in patients from Russia by APEX technology.
Neurosci
Lett. 2006 Sep 25;405(3):212-6. Epub 2006 Jul 28. PDF
|
|
12.
|
Oselin
K, Anier K, Tamm R, Kallassalu K, Maeorg U.
Determination of thiopurine S-methyltransferase (TPMT)
activity by comparing various normalization factors:
reference values for Estonian population using HPLC-UV
assay.
J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Apr
13;834(1-2):77-83.
|
|
13.
|
Lahermo
P, Liljedahl U, Alnaes G, Axelsson T, Brookes A, Ellonen P,
Groop P-E, Halldén C, Holmberg D, Holmberg K, Keinänen M, Kepp
K, Kere J, Kiviluoma P, Kristensen V, Lindgren C,
Odeberg J, Osterman P, Parkkonen M, Saarela J, Sterner M,
Strömqvist L, Talas U, Wessman M, Palotie A, Syvänen A-C
(2006) A Quality Assessment Survey of SNP Genotyping
Laboratories. Hum Mutat, 27(7):711-714 PDF
|
|
14.
|
Zhang J, Kaasik K,
Blackburn MR, Lee CC.
Constant darkness is a circadian metabolic signal in
mammals.
Nature. 2006 Jan
19;439(7074):340-3. PDF
|
|
|
|
|
2005
|
|
|
1.
|
S. Altmäe,
A. Runina, M. Kuningas, T. Kahre, M. Peters, A.
Ehrenberg, H. Karro, A. Salumets, A. Metspalu. 2005.
Loote reesusstaatuse mitte-invasiivne diagnostika -
prenataalse diagnostika uus võimalus Eestis.
Eesti Arst 12/2005: 847-853.
|
|
2.
|
Evaluation
of arrayed primer extension for TP53 mutation detection in
breast and ovarian carcinomas.
Pedro Kringen, Anna Bergamaschi, Eldri Undlien Due, Yun Wang,
Elda Tagliabue, Jahn M. Nesland, Aune Ahman, Neeme
Tõnisson, and Anne-Lise Børresen-Dale.
BioTechniques, vol. 39 , no 5 (2005): pp 755-761 PDF
|
|
3.
|
Haller
K,
Mathieu
C, Rull
K, Matt
K, Bene
MC, Uibo
R. IgG,
IgA and IgM Antibodies against FSH: Serological Markers of
Pathogenic Autoimmunity or of Normal Immunoregulation? Am J
Reprod Immunol. 2005 Nov;54(5):262-9.
|
|
4.
|
Hallast
P,
Nagirnaja L, Margus T,
Laan M.
Segmental
duplications and gene conversion: Human luteinizing hormone/chorionic
gonadotropin {beta} gene cluster.
Genome Res. 2005 Nov;15(11):1535-46.
|
|
5.
|
Rull
K, Laan M.
Expression of {beta}-subunit of HCG genes during normal and
failed pregnancy. Hum Reprod. 2005 Hum. Reprod. 20(12),
3360-3368.
|
|
6.
|
Patsalis
PC, Kousoulidou L, Sismani C, Männik K, Kurg A.
MAPH: from gels to microarrays.
Eur J
Med Genet. 2005 Jul-Sep;48(3):241-9.
|
|
7.
|
Schrijver I, Oitmaa E, Metspalu A,
Gardner P.
Genotyping Microarray for the Detection of More Than 200 CFTR
Mutations in Ethnically Diverse Populations. J
Mol Diagn. 2005 Aug;7(3):375-87 PDF
|
|
8.
|
Lamina
C, Steffens M, Mueller J, Lõhmussaar
E, Meitinger T, Wichmann HE.
Genetic diversity in german and European populations:
looking for substructures and genetic patterns.
Gesundheitswesen. 2005 Aug;67 Suppl 1:S127-31.
|
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9.
|
Eensaar R, Metspalu A, L'Estonie
parie sur les biotechnologies. Biofutur 257: 51-54.
|
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10.
|
Le Calvez F,
Ahman A, Tonisson N, Lambert J, Temam S, Brennan P,
Zaridze DG, Metspalu A, Hainaut P.
Arrayed Primer Extension Resequencing of Mutations in the
TP53 Tumor Suppressor Gene: Comparison with Denaturing HPLC
and Direct Sequencing.
Clin Chem. 2005
Jul;51(7):1284-7.
|
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11.
|
Koks S, Nikopensius
T, Koido K, Maron E, Altmae S, Heinaste E, Vabrit K,
Tammekivi V, Hallast P, Kurg A, Shlik J, Vasar V, Metspalu
A, Vasar E.
Analysis of SNP profiles in patients with major depressive
disorder.
Int.
J. Neuropsychopharmacol. 2005 Jun 1,pp. 1-8 PDF
|
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12.
|
Maron
E., Nikopensius T., Kõks S., Altmäe S., Heinaste
E., Vabrit K., Tammekivi V., Hallast P., Koido K., Kurg A.,
Metspalu A., Vasar E., Vasar V., Shlik J.
Association
study of 90 candidate gene polymorphisms in panic disorder.
Psychiatric Genet., 2005, 15(1):17-24. PDF
|
|
13.
|
Laan
M, Wiebe V, Khusnutdinova E, Remm M, Paabo S.
X-chromosome
as a marker for population history: linkage disequilibrium
and haplotype study in Eurasian populations. Eur
J Hum Genet. 2005 Apr;13(4):452-62.
PDF
|
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14.
|
Dean
M, Annilo T.
Evolution of the ATP-binding cassette (ABC) transporter
superfamily in vertebrates. Annu Rev Genomics Hum Genet.
2005;6:123-42.
|
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15.
|
Lõhmussaar
E,
Gschwendtner A, Mueller JC, Org T, Wichmann E, Hamann G,
Meitinger T, Dichgans M.
ALOX5AP gene and the PDE4D gene in a central European
population of stroke patients. Stroke. 2005 Apr;36(4):731-6.
Epub 2005 Feb 24
|
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16.
|
Jakob C. Mueller*,
Elin Lõhmussaar*, Reedik Mägi, Maido Remm, Thomas
Bettecken, Peter Lichtner, Saskia Biskup, Thomas Illig, Arne Pfeufer,
Jan Luedemann, Stefan Schreiber, Peter Pramstaller, Irene Pichler,
Giovanni Romeo, Anthony Gaddi, Alessandra Testa, Heinz-Erich Wichmann,
Andres Metspalu and Thomas Meitinger. Linkage
disequilibrium patterns and tagSNP transferability among European
populations. Am J Hum Genet 2005 Jan 6;76 (3). PDF
|
|
2004
|
|
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1.
|
Koido K., Kõks S., Nikopensius T.,
Maron E., Altmäe S., Heinaste E., Vabrit K., Tammekivi V., Hallast
P., Kurg A., Shlik J., Vasar V., Metspalu A., Vasar E.
Polymorphisms in wolframin (WFS1) gene are possibly related to
increased risk for mood disorders. Int. J. Neuropsychopharmacol.,
2005, 8(2): 235-244. PDF
|
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2.
|
Andres Metspalu (2004), “The Estonian Genome Project”, Drug
Development Research 62: 97-101.PDF
|
|
3.
|
Kaasik K., Lee
CC., "Reciprocal
regulation of haem biosynthesis and the circadian clock in mammals.",
Nature. 2004 Jul 22;430(6998):467-71.
|
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4.
|
K Kingo, S Koks, T Nikopensius, H Silm and E Vasar
Polymorphisms in the interleukin-20 gene: relationships to
plaque-type psoriasis
Genes and Immunity, Vol 5 (2004): 117–121. |
|
5.
|
Kahre,
T., Teder, M., Panov, M., Metspalu, A., "Severe
CF manifestation with anaemia and failure to thrive in a 394delTT
homozygous patient. Journal of Cystic Fibrosis, Vol 3
(2004): 58-60. PDF |
|
6.
|
Salumets, A.,
Horelli-Kuitunen, N., Suikkari, A-M.,
Metspalu, A., Tuuri, T. "Elevated incidence of
chromosomally chaotic embryos among frozen-thawed preimplatation
embryos." Eur. J. Obstetrics & Gynecology and Reproductive
Biology, Vol 114, Issue 1, (2004): 59-63. |
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7.
|
Metspalu,
A., Köhler, F., Laschinski, G., Ganten, D., Roots, I.,
"Das estnische Genomprojekt in Kontext der europäischen
Genomforschung", Dtsch. Med. Wochenschr
2004;129:S25-S28. |
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8.
|
Salumets
A, Horelli-Kuitunen N, Suikkari AM, Metspalu A, Tuuri T.
Elevated incidence of chromosomally chaotic embryos among frozen-thawed
preimplantation embryos.
Eur J Obstet Gynecol Reprod Biol. 2004 May 10;114(1):59-63. |
|
9. |
J.
Pullat, M. Beier, M. Dahms, E. de Villiers, J. Hoheisel.
Simultaneous typing of HPV strains by microarray analysis,
European Journal of Human Genetics Vol. 10, Suppl 1, 2004,
P1124 |
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1.
|
Lamba,
J.K., Adachi, M., Sun, D., Tammur, J., Schuetz,
E.G.,
Allikmets, R. and Schuetz, J.D. "Nonsense mediated decay
downregulates
conserved alternatively spliced ABCC4 transcripts bearing
nonsense
codons." Human Molecular Genetics 2, Vol. 12 (2003):
99-109. |
|
2.
|
Murumägi,
A., Vähämurto, P., and Peterson, P. "Characterization
of Regulatory Elements and Metylation Pattern of the Autoimmune
Regulator (AIRE) Promoter." The Journal of Biological
Chemistry 22, Vol. 278 (2003): 19784-19790. PDF |
|
3.
|
Tätte,
T., Saal, K., Kink, I., Kurg, A., Lõhmus, R.,
Mäeorg, U., Rahi, M., Rinken, A., Lõhmus, A. "Preparation
of smooth siloxane surfaces for AFM visualization of immobilized
biomolecules." Surface Science 532-533 (2003): 1085-1091. |
|
4.
|
Talkop,
U-A., Kahre, T., Napa, A., Talvik, I., Sööt,
A., Piirsoo, A., Sander, V., Talvik, T. "A descriptive
epidemiological study of Duchenne muscular dystrophy in childhood
in Estonia" European Journal of Pediatric Neurology (2003)
7, 221-226. |
|
5.
|
Jaakson,
K., Zernant, J., Külm, M., Hutchinson, A., Tõnisson,
N., Glavac, D., Ravnik-Clavac, M., Hawlina, M., Meltzer,
M.R., Caruso, R.C., Testa, F., Maugeri, A., Hoyng, C.B.,
Gouras,
P., Simonelli, F., Lewis, R.A., Lupski, J.R., Cremers, F.P.M.,
Allikmets, R. "Genotyping Micoarray (Gene Chip) for the
ABCR (ABCA4) Gene". Human Mutation 22 (2003): 395-403. |
|
6.
|
Bauer, A.,
Beckmann, B., Busold, C., Brandt, O., Kusnezow, W., Pullat,
J., Aign, V., Fellenberg, K., Fleischer, R., Jacob, A.,
Frohme, M. & Hoheisel, J.D. “Use of complex DNA- and
antibody-microarrays as tools in functional analyses”. Comp.
Funct. Genom., (2003) 4:520-524. PDF |
|
7.
|
Metspalu, A. “Microarrays and Single
Nucleotide Polymorphism (SNP) genotyping”. In: Nature
Encyclopedia of the Human Genome. Nature Publishing Group.
2003. pp. 921-925. |
|
8.
|
Remm,
M., Kurg, A. Metspalu, A. PCR Technology: Current Innovations,
2nd Edition. pp: 131-140. CRC Press, USA, November 2003. ISBN
0-8493-1184-5 |
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1.
|
Zhang,
X., Hargitai, J., Tammur, J., Hutchinson, A.,
Allikmets,
R., Chang, S., Gouras, P. "Macular pigment and visual
acuity in
Stargardt macular dystrophy." Graefes Arch Clin Exp Ophthalmol
240
(2002):802-809. DOI 10.1007/s00417-002-0554-z |
|
2.
|
Rebane
A, Roomere H, Metspalu A. "Locations of several novel
2'-O-methylated nucleotides in human
28S rRNA." BMC Molecular Biology 2002, 3:1 (14 February
2002) PDF |
|
3.
|
Metspalu
A." Genes, technology and public dialogue in Tartu,
Estonia" Trends in Biotechnology 2002, Feb;2:51-52. PDF |
|
4.
|
Tõnisson N., Zernant J., Kurg A.,
Pavel H., Slavin G., Roomere H., Meiel A.,
Hainaut P. and Metspalu A.. “Evaluating
the arrayed primer extension resequencing assay of TP53 tumor
suppressor gene”. Proc. Natl. Acad. Sci. USA, 2002, Vol.
99, Issue 8, 5503-5508. PDF |
|
5.
|
Maugeri,
A., Flothmann, K., Hemmrich, N., Ingvast, S., Jorge, P.,
Paloma,
E., Patel, R., Rozet J.M., Tammur, J., Testa, F.,
Balcells,
S., Bird, A.C., Brunner, H.G., Hoyng, C.B., Metspalu, A.,
Simonelli, F., Allikmets, R., Bhattacharya, S.S., D'Urso,
M., Gonzàlez-Duarte, R., Kaplan, J., te Meerman, G.J.,
Santos, R., Schwartz, M., Camp G.V., Wadelius, C., Weber,
B.H.F., and Cremers, F.P.M. "The ABCG4 2588 G>C Stargardt
mutation: single origin and increasing frequency from South-West
to North-East Europe". Eur J Hum Genet. 2002, 10: 197-203. |
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6.
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Kaessmann
H, Zöllner S, Gustafsson A, Wiebe V, Laan M, Lundeberg
J, Uhlen M, Pääbo S (2002) Extensive linkage disequilibrium
in small human populations in Eurasia. Am J Hum Genet.,70,
673-685 |
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7.
|
Laan
M, Richmond H, Chaomei He, Campbell R (2002) Zebrafish
as a model for vertebrate reproduction: Characterization of
the first functional zebrafish (Danio rerio) gonadotropin
receptor. Gen Comp Endocrinol., 125, 349-364. |
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8.
|
Tammur
J, Sibul H, Ustav E, Ustav M, Metspalu A. “A
bovine papillomavirus-1 based vector restores the function
of the low-density lipoprotein receptor in the receptor-deficient
CHO-IdIA7 cell line” BMC Molecular Biology 2002, 3:5.
ISSN 1471-2199. PDF |
|
9.
|
Andres
Metspalu comment to: Pálsson, G. and Hardardóttir
"For Whom the Cell Tolls" Current Anthropology 43,
2, April 2002: 292. |
|
10.
|
Andres
Metspalu "Biotechnology as an instrument of politics:
the example of Estonia. 17th Sinclair House debate "Who
owns the human genome?" Herbert Quandt Foundation, March
2002: 43-45. ISBN 3-00-008926-8 |
|
11.
|
Jafar
Mahdavi, Berit Sondén, Marina Hurtig, Farzad O. Olfat,
Lina Forsberg, Niamh Roche, Jonas Ångström, Thomas
Larsson, Susann Teneberg, Karl-Anders Karlsson, Siiri
Altraja, Torkel Wadström, Dangeruta Kersulyte,
Douglas E. Berg, Andre Dubois, Christoffer Petersson, Karl-Eric
Magnusson, Thomas Norberg, Frank Lindh, Bertil B. Lundskog,
Anna Arnqvist, Lennart Hammarström, and Thomas Borén
“Helicobacter pylori SabA Adhesin in Persistent Infection
and Chronic Inflammation”, Science 2002 July 26; 297:
573-578. PDF |
|
12.
|
Elisabeth
Dawson, Gonçalo R. Abecasis, Suzannah Bumpstead, Yuan Chen,
Sarah Hunt, David M. Beare, Jagjit Pabial, Thomas Dibling,
Emma Tinsley, Susan Kirby, David Carter, Marianna
Papaspyridonos, Simon Livingstone, Rocky Ganske, Elin Lõhmussaar,
Jana Zernant, Neeme Tõnisson, Maido
Remm, Reedik Mägi, Tarmo Puurand, Jaak
Vilo, Ants Kurg, Kate Rice, Panos Deloukas,
Richard Mott, Andres Metspalu, David R.
Bentley, Lon R. Cardon, Ian Dunham “A first-generation
linkage disequilibrium map of human chromosome 22”, Nature
418, 544 - 548 (01 Aug 2002) PDF |
|
13.
|
Gemignani,
F., Perra, C., Landi, St., Canzian, F., Kurg, A., Tõnisson,
N., Galanello, R., Cao, A., Metsplau, A. and
Romeo,
G. "Reliable detection of b-Thalassemia and G6PD mutations
by a DNA microarray." Clinical Chemistry 48 No. 11 (2002):
2051-2054. PDF |
|
14.
|
Annilo,
T., Tammur, J., Hutchinson, A.,
Rzhetsky,
A., Dean, M.
and Allikmets, R. "Human mouse orthologs of a new ATP-binding
cassette
gene, ABCG4." Cytogenetics and cell Genetics 94 (2001):
196-201. |
|
15.
|
Metspalu A.
Estonian Genome Project-before the take-off and take-off.
Bioinformatics. 2002 Oct;18 Suppl 2:S152. |
|
16.
|
Kurzawski
G, Suchy J, Kladny J, Safranow K, Jakubowska A, Elsakov P,
Kucinskas V, Gardovski J, Irmejs A, Sibul H, Huzarski
T, Byrski T, Debniak T, Cybulski C, Gronwald J, Oszurek O,
Clark J, Gozdz S, Niepsuj S, Slomski R, Plawski A, Lacka-Wojciechowska
A, Rozmiarek A, Fiszer-Maliszewska L, Bebenek M, Sorokin D,
Stawicka M, Godlewski D, Richter P, Brozek I, Wysocka B, Jawien
A, Banaszkiewicz Z, Kowalczyk J, Czudowska D, Goretzki PE,
Moeslein G, Lubinski J. "Germline MSH2 and MLH1 mutational
spectrum in HNPCC families from Poland and the Baltic States."
J Med Genet. 2002 Oct;39(10):E65 |
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1.
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Tammur,
J., Prades, C., Arnould, I.,
Rzhetsky, A., Hutchinson,
A., Adachi, M., Schuetz, J.D., Swoboda, K.J., Ptacek, L.J.,
Rosier, M., Dean, M., and Allikmets, R. Two new genes from
the human ATP-binding cassette transporter superfamily, ABCC11
and ABCC12, tandemly duplicated on chromosome 16q12. Gene
(2001) 273(1):89-96. |
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2.
|
Bernstein,
P.S., Tammur, J., Singh, N., Hutchinson, A., Dixon,
M., Pappas, C.M., Zabriskie, N.A., Zhang, K., Petrukhin, K.,
Leppert, M., and Allikmets, R. Diverse macular dystrophy phenotype
caused by a novel complex mutation in the ELOVL4 gene. Invest.
Ophthalmol. Vis. Sci. (2001) 42(13):3331-3336. |
|
3.
|
Ayyagari
R, Zhang K, Hutchinson A, Yu Z, Swaroop A, Kakuk LE, Seddon
JM, Bernstein PS, Lewis RA, Tammur J, Yang Z, Li Y,
Zhang H, Yashar BM, Liu J, Petrukhin K, Sieving PA, Allikmets
R. Evaluation of the ELOVL4 gene in patients with age-related
macular degeneration. Ophthalmic Genet. (2001) 22(4):233-239. |
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4.
|
Vaher
U, Napa A, Nurmiste A, Piirsoo A, Sibul H, Talvik T.
Four siblings with Hallervorden-Spatz disease. Brain Dev.
2001 Jul;23(4):236-9. |
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5.
|
Wittig
I, Augstein P, Brown GK, Fujii T, Rotig A, Rustin P, Munnich
A, Seibel P, Thorburn D, Wissinger B, Tamboom K, Metspalu
A, Lamantea E, Zeviani M, Wehnert MS. Sequence variations
in the NDUFA1 gene encoding a subunit of complex I of the
respiratory chain. Journal Inherited Metabolic Diseases 2001
Feb;24(1):15-27. |
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6.
|
Gerhard
M, Hirmo S, Wadström T, Miller-Podraza
H, Teneberg S, Karlsson K-A, Appelmelk B, Odenbreit S, Haas
R, Arnqvist A, Borén T. 2001. H. pylori, an adherent
pain in the stomach. In: Helicobacter pylori: Molecular and
Cellular Biology (Achtman M, Suerbaum S, Eds.) Horizon Scientific
Press, Norfolk, U.K. Chapter 12. |
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7.
|
Arnqvist
A, Ilver D, Ögren J, Hirmo S, Wadström
T, Borén T. 2001. Adherence of Helicobacter pylori:
Mechanisms and Relevance to Pathogenesis. In: Pathogenesis
and Host Response in Helicobacter pylori Infections (Moran
AP, O'Morain CO, Eds.) Normed Verlag Inc, Englewood, NJ, USA.
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8.
|
Wang
X, Hirmo S, Willén R, Wadström T. 2001.
Inhibition of Helicobacter pylori infection by bovine milk
glycoconjugates in a Balb/cA mouse model. J Med Microbiol
50: 430-435. |
|
9.
|
Remm,
M. and A. Metspalu. "High-density genotyping and
linkage disequilibrium in the human genome using chromosome
22 as a model". Current Opinion in Chemical Biology,
2001, 6:24-30. PDF |
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1.
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Tõnisson,
N., Kurg, A., Lõhmussaar, E., Metspalu, A. Arrayed
primer extension on the DNA chip - method and applications.
In "DNA Microarrayes: Biology and Technology" Ed by M. Schena
(2000) BioTechniques Books ISBN 1-881299-37-6, 247-263. PDF |
|
2.
|
Hahn,
D., Ilisson, R., Metspalu, A. and Sterchi, E.E. Human
N-benzoyl-L-Tyrosyl-p-Aminobenzoic Acid Hydrolase (human
meprin):
genomic structure of alpha and beta subunits. Biochemical
Journal (2000) 346, 83-91. |
|
3.
|
Kurg,
A., Tõnisson, N.,
Georgiou, I., Shumaker, J., Tollett,
J., Metspalu, A. Arrayed Primer Extension: Solid phase
four-color DNA resequencing and mutation detection technology
(2000) Genetic Testing 4(1), 1-7. PDF |
|
4.
|
Gasparini,
P., Rabionet, R., Barbujani, G., Melchionda, S., Petersen,
M., Brondum-Nielsen, K., Metspalu, A., Oitmaa, E.,
Pisano, M., Fortina, P., Zelante, L., Estivill, X. High carrier
frequency of the 35delG deafness mutation in European populations.
Genetic Analysis Consortium of GJB2 35delG. Eurpean Journal
of Human Genetics (2000) 8 (1), 19-23 |
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5.
|
Tõnisson
N, Kurg A, Kaasik K, Lõhmussaar E, Metspalu A.
Unravelling Genetic Data by Arrayed Primer Extension. Clinical
Chemistry and Laboratory Medicine 2000, 38 (2), 165-177. By
Walter de Gruyter, Berlin, New York. PDF |
|
6.
|
T.
Dörk, M. Macek, F. Mekus, B. Tümmler, J.
Tzountzouris,
T. Casals, A. Krebsova, M. Koudova, I. Sakmaryova, M. Macek
Sr, V. Vavrova, D. Zemkova, E. Ginter, N.V. Petrova, T.
Ivaschenko,
V. Baranov, M. Witt, A. Pogorzelski, T. Neumann, S.
Jakubiczka, C. Kraus, B. Thamm, M. Nechiporenko, L. Livshits,
N. Mosse, G. Tsukerman, L. Kadasi, M. Ravnik-Glava, R. Komel,
K. Vouk, V. Kuzinskas, A. Krumina, M. Teder, S.
Kocheva, G.D. Efremov, T. Onay, B. Kirdar, G. Malone, M. Schwarz, Z.
Zhou, K.J. Friedman, S. Carles, M. Claustres, D. Bozon, C.
Verlingue, C. Ferec, M. Tzetis, E. Kanavakis, H. Cuppens,
C. Bombieri, P.F. Pignatti, F. Sangiuolo, A. Jordanova, J.
Kusic, D. Radojkovi?, J. Serti, D. Richter, A. Stavljeni?
Rukavina, E. Bjorck, B. Strandvik, H. Cardoso, M. Montgomery,
B. Nakielna, D. Hughes, X. Estivill, I. Aznarez, E. Tullis,
L-C. Tsui, J. Zielenski. Charecterization of a novel 21-kb
deletion, CFTRdel2,3(21 kb), in the CFTR gene: a cystic fibrosis
mutation of Slavic origin common in Central and East Europe
(2000) Hum Genet 106, 259-268. DOI 10.1007/s004390000246 |
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7.
|
Teder,
M., Klaassen, T., Oitmaa, E., Kaasik, K. and Metspalu,
A. Distribution of the CFTR gene mutations in cystic fibrosis
patients from Estonia (2000) Journal of Medical Genetics 37
(http://jmedgenet.com/cgi/content/full/37/8/e16) |
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8.
|
Varilo
T, Laan M, Hovatta I, Wiebe V, Terwilliger JD and Peltonen
L (2000)
Linkage disequilibrium
and the demographic history of isolated populations:
Finland and a young
subpopulation of Kuusamo. Eur J Hum Genet 8: 604-612 |
|
9.
|
Auffray,
C., Mundy, C. and Metspalu, A. DNA arrays: method and
applications: report on HUGO Meeting, Tartu, Estonia, 23-26
May, 1999. European Journal of Human Genetics (2000) 8, 236-238. |
| |
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1.
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Metspalu,
A and Shumaker, J.M. "DNA resequencing, mutation detection
and gene expression analysis by oligonucleotide microchips"
In: "Microsystems Technology: A Powerful Tool for Biomolecular
Studies" ed. by M. Köhler et al. (1999) Birkhaeuser Verlag,
371-397. |
|
2.
|
Tensing,
K., Pata, I., Wittig, I., Wehnert, M., and Metspalu,
A. Genomic organization of the human Complex I13kDa subunit
gene NDUFA5 (1999) Cytogenetics and Cell Genetics 84, 125-127. |
|
3.
|
Rebane,
A. and Metspalu, A. U821, a novel snoRNA identified from
the fifth intron of human and mousenucleon gene (1999) Biochimica
et Biophysica Acta 1446, 426-430. |
|
4.
|
Ü.A.
Talkop, T. Klaassen, A. Piirsoo, V. Sander, , A. Napa,
E. Essenson, J. Tammur, T. Talvik "Early clinical
symptoms of Duchenne muscular dystrophy in correlation with
DNA diagnostics and immunochemical analysis" (1999) Brain
and Development 21, 244-247.
|
|
5.
|
Ü.A.
Talkop, M. Sõnajalg, A. Paves, H. Sibul, A.
Piirsoo, T. Talvik "Kardiomüopaatia Duchenne'i ja Beckeri
tüüpi lihasdüstroofiaga lastel" (1999) Eesti
Arst 2, 107-110.
|
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6.
|
Auffray C, Mundy C,
Metspalu A. DNA arrays: methods and applications: report on HUGO Meeting, Tartu,
Estonia.
23-26 May, 1999.Eur J Hum Genet. 2000 Mar;8(3):236-8.
|
|
7.
|
Hardo Lilleväli,
Külli Margus, Katrin Õunap and Andres Metspalu
Mutation 985A>G in the MCAD Gene Shows Low Incidence
in Estonian Population
HUMAN MUTATION Mutation in Brief #295 (1999) Online
|
|
8.
|
Metspalu,
A., Kaasik, K., Tõnisson, N., & Kurg, A. (1999).
Oligonucleotide Array for Mutation Analysis in Familial
Breast Cancer. Disease Markers, 15(1-3), 117.
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1998
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|
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1.
|
Õunap,
K., H. Lilleväli, A. Metspalu, M. Sitska-Lipping.
Development of phenylketonuria screening program in Estonia.
(1998) Journal of Medical Screening 4, 00-00. |
|
2.
|
Klaassen,
T., M. Teder, M. Viikmaa, A. Metspalu. Neonatal
screening for the cystic fibrosis main mutation D F508 in
Estonia: A pilot study. (1998) Journal of Medical Screening
5 |
|
3.
|
Rebane,
A., Tamme, R., Laan, M., Pata, I. and Metspalu,
A. A novel snoRNA (U73) is encoded within the introns
of the human and mouse ribosomal proteins S3a genes. (1998)
Gene. |
|
4.
|
Stephens,
J.C., Reich, D.E., Goldstein, D.B., Shain, H.D., Smith, M.W.,
Carrington, M., Winkler, C., Huttley, G.A., Allikmets, R.,
Schriml, L., Gerrard, B., Malasky, M., Ramos, M.D., Morlot,
S., Tzetis, M., Oddoux, C., di Giovine, F.S., Nasioulas, G.,
Chandler, D., Aseev, M., Hanson, M., Kalaydjieva, L., Glavac,
D., Gasparini, P., Kanavakis, E., Claustres, M., Kambouris,
M., Ostrer, H., Duff, G., Baranov, V., Sibul, H., Metspalu,
A., Goldman, D., Martin, N., Duffy, D., Schmidtke, J.,
Estevill, X., O’Brien, S.J., Dean, M. “Dating the Origin of
the CCR5-Delta32 AIDS-Resistance Allele by the Coalescence
of Haplotypes” (1998) Am. J. Hum. Genet. 62(6), 1507-1515. |
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5.
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Metspalu,
A., Saulep, H., Kurg, A., Tõnisson, N., Shumaker,
J.M. (1998) Primer extension from two-dimensional oligonucleotides
grid for DNA sequencing analysis. In: Genomics: Commercial
opportunities from a scientific revolution. BIOS Scientific
Publishers. Edited by G. K. Dixon, L. G. Copping, D. Livingstone.
217-219 |
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6.
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Annilo,
T., Karis, A., Hoth, S., Rikk, T., Kruppa, J., Metspalu,
A. “Nuclear import and nucleolar accumulation of the human
ribosomal protein S7 depend on both a minimal nuclear localization
sequence and adjacent basic region”. (1998) Biochemical and
Biophysical Research Communications. Volume 249, No. 3, Aug
28, 1998 |
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7.
|
Annilo,T.,
Jelina, J., Pata, I., and Metspalu, A. “Isolation and
characterization of a mouse ribosomal protein S7 gene” (1998)
Biochemistry and Molecular Biology International. 46(2), 287-295 |
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1.
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Pata,
I., Tensing, K. and Metspalu, A.
A human cDNA encoding the homologue of NADH: ubiquinone oxidoreductase
subunit B13. (1997) Biochimica et Biophysica Acta 1350/2,
115-118. |
|
2.
|
Pastinen,
T., Kurg, A., Metspalu, A.,
Peltonen, L. and Syvänen, A.-C. Minisequencing: A specific
tool for DNA analysis and diagnostics on oligonucleotide arrays.
(1997) Genome Research 7 ,606-614. |
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3.
|
Ilisson,
R., Pata, I.Kurg, A., Beier, D.,
Marquart, O. and Ebner, D. Provirus Mutants of the Bovine
Leukaemia Virus and their Relation to the Serological Status
in Naturally Infected Cattle. (1997) Virology 237, 261-269 |
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1.
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Fechner,
H., Kurg, A., Blankenstein, P., Mewes, G., Geue, L.,
Albrecht, C. and Ebner, D. Direct use of cell lysates in PCR-based
diagnosis of bovine leukaemia virus infection. (1996) Berl.
Münch. Tierärztl. Wschr. 109, 446-450. |
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2.
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Fechner,
H., Kurg, A., Geue, L., Blankenstein, P., Mewes, G.,
Ebner, D. and Bsier, D. Evaluation of Polymerase Chain Reaction
(PCR) Application in Diagnosis of Bovine Leukaemia Virus (BLV)
Infection in Naturally Infected Cattle. (1996) Journal of
Veterinary Medicine B 43, 621-630. |
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3.
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Shumaker,
J.M., Metspalu, A., Caskey, T.C. Mutation Detection
by Solid Phase Primer Extension. (1996) Human Mutation 7,
346-354. |
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4.
|
Shumaker,
J.M., Metspalu, A. and Caskey C.T. “Multiplex solid-phase
fluorescent primer extension” In "Laboratory protocols for
mutation detection" Ed. by Landegren, Ulf, Oxford University
Press (1996) 93-95. |
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5.
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Õunap,
K., Lilleväli, H., Klaassen, T., Metspalu, A. and
Sitska, M. Short Report. The incidence and characterization
of phenylketonuric patients in Estonia. (1996) J. Inher. Metab.
Dis. 19, 381-382. |
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6.
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Pata,
I. and Metspalu, A. Structural characterization
of the mouse ribosomal protein S6-encoding gene. (1996) Gene
175, 241-245. |
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7.
|
Lilleväli,
H., Õunap, K. and Metspalu, A. Phenylalanine
hydroxylase gene mutation R408W is present on 84% of Estonian
phenylketonuria chromosomes. (1996) European Journal of Human
Genetics 4, 296-300. |
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1.
|
Annilo,
T., Laan, M., Stahl, J., Metspalu, A. Human ribosomal
protein S7 gene - isolation, structure and location in 2p25.
(1995) Gene 165, 297-302. |
|
2.
|
Kurg,
A., Sommer, G., and Metspalu, A. An RNA Stem-Loop
Structure Involved in the Packaging of Bovine leukaemia Virus
Genomic RNA in vivo. (1995) Virology 211, 434-442. |
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3.
|
Shumaker,
J.M., Metspalu, A., Ngo, T.T., Caskey, C.T. Primer
Extension Mutation Detection Method: A Non-Gel Based Method
for Rapid Mutation Identification. (1995) The Fifth International
Symposium on Human Identification 1994, 147-151. ISBN 1-882274-54-7. |
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