Josine L. Min, George Nicholson, Ingileif Halgrimsdottir, Kristian Almstrup, Andreas Petri, Amy Barrett, Mary Travers, Nigel W. Rayner, Reedik Mägi, Fredrik H. Pettersson, John Broxholme, Matt J. Neville, Quin F. Wills, Jane Cheeseman, The GIANT Consortium", The MolPAGE Consortium", Maxine Allen, Chris C. Holmes, Tim D. Spector, Jan Fleckner, Mark I. McCarthy, Fredrik Karpe, Cecilia M. Lindgren, Krina T. Zondervan

Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes
PLoS Genetics, February 2012 | Volume 8 | Issue 2, PDF
 

6. Jonathan P Bradfield, H Rob Taal, Nicholas J Timpson, André Scherag, Cecile Lecoeur, Nicole M Warrington, Elina Hypponen, Claus Holst, Beatriz Valcarcel, Elisabeth Thiering, Rany M Salem, Fredrick R Schumacher, Diana L Cousminer, Patrick M A Sleiman, Jianhua Zhao, Robert I Berkowitz, Karani S Vimaleswaran, Ivonne Jarick, Craig E Pennell, David M Evans, Beate St Pourcain, Diane J Berry, Dennis O Mook-Kanamori, Albert Hofman, Fernando Rivadeneira, André G Uitterlinden, Cornelia M van Duijn, Ralf J P van der Valk, Johan C de Jongste, Dirkje S Postma, Dorret I Boomsma, W James Gauderman, Mohamed T Hassanein, Cecilia M Lindgren, Reedik Mägi, Colin A G Boreham, Charlotte E Neville, Luis A Moreno, Paul Elliott, Anneli Pouta, Anna-Liisa Hartikainen, Mingyao Li, Olli Raitakari, Terho Lehtimäki, Johan G Eriksson, Aarno Palotie, Jean Dallongeville, Shikta Das, Panos Deloukas, George McMahon, Susan M Ring, John P Kemp, Jessica L Buxton, Alexandra I F Blakemore, Mariona Bustamante, Mònica Guxens, Joel N Hirschhorn, Matthew W Gillman, Eskil Kreiner-Møller, Hans Bisgaard, Frank D Gilliland, Joachim Heinrich, Eleanor Wheeler, Inês Barroso, Stephen O’Rahilly, Aline Meirhaeghe, Thorkild I A Sørensen, Chris Power, Lyle J Palmer, Anke Hinney, Elisabeth Widen, I Sadaf Farooqi, Mark I McCarthy, Philippe Froguel, David Meyre, Johannes Hebebrand, Marjo-Riitta Jarvelin, Vincent W V Jaddoe, George Davey Smith, Hakon Hakonarson & Struan F A Grant for the Early Growth Genetics (EGG) Consortium
A genome-wide association meta-analysis identifies new childhood obesity loci
Nature Genetics, Published Online 15. April 2012
http://www.nature.com/ng/journal/vaop/ncurrent/pdf/ng.2247.pdf   PDF
  

4. Luciano M, Lopez LM, de Moor MH, Harris SE, Davies G, Nutile T, Krueger RF, Esko T, Schlessinger D, Toshiko T, Derringer JL, Realo A, Hansell NK, Pergadia ML, Pesonen AK, Sanna S, Terracciano A, Madden PA, Penninx B, Spinhoven P, Hartman CA, Oostra BA, Janssens AC, Eriksson JG, Starr JM, Cannas A, Ferrucci L, Metspalu A, Wright MJ, Heath AC, van Duijn CM, Bierut LJ, Raikkonen K, Martin NG, Ciullo M, Rujescu D, Boomsma DI, Deary IJ.
Longevity candidate genes and their association with personality traits in the elderly.
Am J Med Genet B Neuropsychiatr Genet. 2012 Mar;159B(2):192-200. doi: 10.1002/ajmg.b.32013. Epub 2011 Dec 27. PDF

5. Liis Leitsalu, Laura Hercher, Andres Metspalu
Giving and Withholding of Information following Genomic Screening: Challenges Identified in a Study of Primary Care Physicians in Estonia
J Genet Counsel, DOI 10.1007/s10897-011-9424-3, Published on-line 08.12.11, PDF
 

13. jaanuar Cheng Luo
20. jaanuar Tiit Nikopensius
27. jaanuar Liis Leitsalu-Moynihan
3. veebruar Tarmo Annilo
10. veebruar Maris Teder-Laving
17. veebruar Anu Tammiste
2. märts Margit Nõukas
9. märts Evelin Mihailov
16. märts Marina Koltšina
23. märts Egon Urgard
30. märts Neeme Tõnisson
4. mai Olga Tšuiko
11. mai Natalia Tšernikova
18. mai Maris Alver
 

1. The International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS) [co-authors from IMBC: University of Tartu Tõnu Esko, Maris Laan, Toomas Haller, Elin Org, Siim Sõber, Andres Metspalu] (2011) Genome‐Wide Association Study of Pulse Pressure and Mean Arterial Pressure Identifies Seven Novel Loci.
Nature genet 43(10): 1005-11

2. Chambers JC et al ... T. Esko, R. Mägi, A. Metspalu
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Nat Genet. 2011 Oct 16;43(11):1131-8. doi: 10.1038/ng.970.

3. Gieger C t al ... T. Esko, R. Mägi, A. Metspalu
New gene functions in megakaryopoiesis and platelet formation.
Nature. 2011 Nov 30;480(7376):201-8. doi: 10.1038/nature10659.

4. Ellinghaus E, Stuart PE, Ellinghaus D, Nair RP, Debrus S, Raelson JV, Belouchi M, Tejasvi T, Li Y, Tsoi LC, Onken AT, Esko T, Metspalu A, Rahman P, Gladman DD, Bowcock AM, Helms C, Krueger GG, Koks S, Kingo K, Gieger C, Wichmann HE, Mrowietz U, Weidinger S, Schreiber S, Abecasis GR, Elder JT, Weichenthal M, Franke A.
Genome-Wide Meta-Analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL.
J Invest Dermatol. 2011 Dec 15. doi: 10.1038/jid.2011.415.

5. CM Middeldorp, MHM de Moor, LM McGrath, SD Gordon, DH Blackwood, PT Costa, A Terracciano, RF Krueger, EJC de Geus, DR Nyholt, T Tanaka, T Esko, PAF Madden, J Derringer, N Amin, G Willemsen, J-J Hottenga, MA Distel M Uda, S Sanna, P Spinhoven, CA Hartman, S Ripke, PF Sullivan, A Realo, J Allik, AC Heath, ML Pergadia, A Agrawal, P Lin, RA Grucza, E Widen, DL Cousminer, JG Eriksson, A Palotie, JH Barnett, PH Lee, M Luciano, A Tenesa, G Davies, LM Lopez, NK Hansell, SE Medland, L Ferrucci, D Schlessinger, GW Montgomery, MJ Wright, YS Aulchenko, ACJW Janssens, BA Oostra, A Metspalu, GR Abecasis, IJ Deary, K Räikkönen, LJ Bierut, NG Martin, NR Wray, CM van Duijn, JW Smoller, BWJH Penninx and DI Boomsma
The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data
Translational Psychiatry (2011) 1, e50; doi:10.1038/tp.2011.45
Published online 18 October 2011 PDF

6. A Terracciano, T Esko, AR Sutin, MHM de Moor, O Meirelles, G Zhu, T Tanaka, I Giegling, T Nutile, A Realo, J Allik, NK Hansell, MJ Wright, GW Montgomery, G Willemsen, J-J Hottenga, M Friedl, D Ruggiero, R Sorice, S Sanna, A Cannas, K Ra¨ikko¨nen, E Widen, A Palotie, JG Eriksson, F Cucca, RF Krueger, J Lahti, M Luciano, JW Smoller, CM van Duijn, GR Abecasis, DI Boomsma, M Ciullo, PT Costa Jr, L Ferrucci, NG Martin, A Metspalu, D Rujescu, D Schlessinger and M Uda
Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking
Translational Psychiatry (2011) 1,e49; doi:10.1038/tp.2011.42
Published online 18 October 2011 PDF

7. Zilina O, Reimand T, Zjablovskaja P, Männik K, Männamaa M, Traat A, Puusepp-Benazzouz H, Kurg A, Ounap K.
Maternally and paternally inherited deletion of 7q31 involving the FOXP2 gene in two families.
Am J Med Genet A. 2011 Nov 21. doi: 10.1002/ajmg.a.34378. PDF
  

8. Metspalu M, Romero IG, Yunusbayev B, Chaubey G, Mallick CB, Hudjashov G, Nelis M, Mägi R, Metspalu E, Remm M, Pitchappan R, Singh L, Thangaraj K, Villems R, Kivisild T.
Shared and unique components of human population structure and genome-wide signals of positive selection in South Asia.
Am J Hum Genet. 2011 Dec 9;89(6):731-44. PDF, Supplement

9. Luciano M, Lopez LM, de Moor MH, Harris SE, Davies G, Nutile T, Krueger RF, Esko T, Schlessinger D, Toshiko T, Derringer JL, Realo A, Hansell NK, Pergadia ML, Pesonen AK, Sanna S, Terracciano A, Madden PA, Penninx B, Spinhoven P, Hartman CA, Oostra BA, Janssens AC, Eriksson JG, Starr JM, Cannas A, Ferrucci L, Metspalu A, Wright MJ, Heath AC, van Duijn CM, Bierut LJ, Raikkonen K, Martin NG, Ciullo M, Rujescu D, Boomsma DI, Deary IJ.
Longevity candidate genes and their association with personality traits in the elderly.
Am J Med Genet B Neuropsychiatr Genet. 2011 Dec 27. doi: 10.1002/ajmg.b.32013. PDF
  

1. The International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS) [co-authors from IMBC: University of Tartu Tõnu Esko, Maris Laan, Toomas Haller, Elin Org, Siim Sõber, Andres Metspalu] (2011) Genome‐Wide Association Study of Pulse Pressure and Mean Arterial Pressure Identifies Seven Novel Loci.
Nature genet 43(10): 1005-11

2. Chambers JC et al ... T. Esko, R. Mägi, A. Metspalu
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Nat Genet. 2011 Oct 16;43(11):1131-8. doi: 10.1038/ng.970.

3. Gieger C t al ... T. Esko, R. Mägi, A. Metspalu
New gene functions in megakaryopoiesis and platelet formation.
Nature. 2011 Nov 30;480(7376):201-8. doi: 10.1038/nature10659.

4. Ellinghaus E, Stuart PE, Ellinghaus D, Nair RP, Debrus S, Raelson JV, Belouchi M, Tejasvi T, Li Y, Tsoi LC, Onken AT, Esko T, Metspalu A, Rahman P, Gladman DD, Bowcock AM, Helms C, Krueger GG, Koks S, Kingo K, Gieger C, Wichmann HE, Mrowietz U, Weidinger S, Schreiber S, Abecasis GR, Elder JT, Weichenthal M, Franke A.
Genome-Wide Meta-Analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL.
J Invest Dermatol. 2011 Dec 15. doi: 10.1038/jid.2011.415.

3. Wang X, Prins BP, Sõber S, Laan M, Snieder H (2011) Beyond Genome-wide Association Studies: New Strategies for Identifying Genetic Determinants of Hypertension. Curr Hypertens Rep 13(6):442-51 (invited review article).

4. Jin H-S, Sõber S, Hong K-W, Org E, Bo-Young Kim B-Y, Laan M, Oh B and Jeong S-Y (2011) Age-dependent association of the polymorphisms in the mitochondria-shaping gene, OPA1, with blood pressure and hypertension in Korean population. Am J Hypertens 24(10):1127-35

5. Org E, Veldre G, Viigimaa M, Juhanson P, Putku M, Rosenberg M, Tomberg K, Uuetoa T, Laan M (2011) HYPEST study: Profile of hypertensive patients in Estonia. BMC Cardiovasc Disord 11:55.
 

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila.
Allebrandt KV, Amin N, Müller-Myhsok B, Esko T, Teder-Laving M, Azevedo RV, Hayward C, van Mill J, Vogelzangs N, Green EW, Melville SA, Lichtner P, Wichmann HE, Oostra BA, Janssens AC, Campbell H, Wilson JF, Hicks AA, Pramstaller PP, Dogas Z, Rudan I, Merrow M, Penninx B, Kyriacou CP, Metspalu A, van Duijn CM, Meitinger T, Roenneberg T.
Mol Psychiatry. 2011 Nov 22. doi: 10.1038/mp.2011.142

2. Surakka I et al ... Esko T, Perola M, Metspalu A.
A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol.
PLoS Genet. 2011 Oct;7(10):e1002333. Epub 2011 Oct 20

3. Wain LV et al ... Esko T, Laan M, Alavere H, Haller T, Tammesoo ML,  Org E, Sõber S, Metspalu A.
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
Nat Genet. 2011 Sep 11;43(10):1005-11. doi: 10.1038/ng.922.

4. Jacquemont S et al ...Esko T, Kurg A, Männik K, Metspalu A.
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus.
Nature. 2011 Aug 31;478(7367):97-102. doi: 10.1038/nature10406.

5. Strawbridge RJ et al ... GIANT Consortium (incl. Andres Metspalu, Maris Teder-Laving, Mari-Liis Tammesoo, Helene Alavere, Mari Nelis).
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
Diabetes. 2011 Oct;60(10):2624-34. Epub 2011 Aug 26.

6. Wichmann HE, Kuhn KA, Waldenberger M, Schmelcher D, Schuffenhauer S, Meitinger T, Wurst SH, Lamla G, Fortier I, Burton PR, Peltonen L, Perola M, Metspalu A, Riegman P, Landegren U, Taussig MJ, Litton JE, Fransson MN, Eder J, Cambon-Thomsen A, Bovenberg J, Dagher G, van Ommen GJ, Griffith M, Yuille M, Zatloukal K.
Comprehensive catalog of European biobanks.
Nat Biotechnol. 2011 Sep 8;29(9):795-7. doi: 10.1038/nbt.1958.

7. Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C.
Systems medicine and integrated care to combat chronic noncommunicable diseases.
Genome Med. 2011 Jul 6;3(7):43.
   

US provisional application no: 61546607, priority date: 13.10.2011, inventors: Anu Tammiste, Lili Milani, Krista Fischer, Tõnu Esko, Kristi Pettai, Kaarel Krjutskov, Reedik Mägi, Merike Leego, Eduard Maron, Andres Metspalu, title of the application: "A Method and a Kit to Predict Response to Antidepressant Treatment"
 

2. Putku M, Kepp K, Org E, Sõber S, Comas D, Viigimaa M, Veldre G, Juhanson P, Hallast P, Tõnisson N, HYPEST, Shaw-Hawkins S, Caulfield MJ, BRIGHT, Khusnutdinova E, Viktor Kožich V, Munroe PB, Laan M (2011) Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans. Hum Mutat, 32(7):806-14.

3. Grigorova M, Punab M, Zilaitiene B, Erenpreiss J, Ausmees K, Matulevicius M, Tsarev I, Jørgensen N, Laan M (2011) Genetically Determined Dosage of Follicle- Stimulating Hormone (FSH) Affects Male Reproductive Parameters. J Clin Endocrinol Metab, 96: E1534-E1541.

4. Eyheramendy S, Gieger C, Laan M, Illig T, Meitinger T, Wichmann E (2011) Effect of genome-wide simultaneous hypotheses tests on the discovery rate. Int J Mol Epidemiol Genet 2(2): 163-77.Org E, Veldre G, Viigimaa M, Juhanson P, Putku M, Rosenberg M, Tomberg K, Uuetoa T, Laan M (2011) HYPEST study: Profile of hypertensive patients in Estonia. BMC Cardiovasc Disord, 11(1):55.Jin H-S, Sõber S, Hong K-W, Org E, Bo-Young Kim B-Y, Laan M, Oh B and Jeong S-Y (2011) Age-dependent association of the polymorphisms in the mitochondria-shaping gene, OPA1, with blood pressure and hypertension in Korean population. Am J Hypertens, advance online publication 28 July 2011; doi:10.1038/ajh.2011.131

5. Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley THJr, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T; International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS) [co-authored by S. Sõber, E. Org, G. Veldre, M. Laan] (2011) Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet 20(11): 2273-84. 
 

Cambon-Thomsen A, Thorisson GA, Mabile L, Andrieu S, Bertier G, Boeckhout M, Cambon-Thomsen A, Carpenter J, Dagher G, Dalgleish R, Deschênes M, di Donato JH, Filocamo M, Goldberg M, Hewitt R, Hofman P, Kauffmann F, Leitsalu L, Lomba I, Mabile L, Melegh B, Metspalu A, Miranda L, Napolitani F, Oestergaard MZ, Parodi B, Pasterk M, Reiche A, Rial-Sebbag E, Rivalle G, Rochaix P, Susbielle G, Tarasova L, Thomsen M, Thorisson GA, Zawati MH, Zins M; BRIF workshop group.
The role of a bioresource research impact factor as an incentive to share human bioresources
Nat Genet. 2011 Jun;43(6):503-4. PDF
  

  5. september Tom Haller
12. september Krista Fischer
19. september Ott Scheler
26. september Lili Milani
  3. oktoober Olga Žilina
10. oktoober Sven Parkel
17. oktoober Cheng Luo
24. oktoober Aune Ahman
31. oktoober Andres Metspalu
  7. november Reedik Mägi
14. november Tõnu Esko
21. november Kaie Kirotar
28. november Kaarel Krjutškov / Mart Kals
  5. detsember Urmo Võsa
12. detsember Riin Tamm
19. detsmber Eva Reinmaa

Igal esinejal palume saata eelnevalt listi oma ettekande pealkiri.

Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, Estrada K, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Kerkhof HJ, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Loughlin J, McCaskie A, Ollier WE, Ralston SH, Spector TD, Wallis GA, Wilkinson JM, Aslam N, Birell F, Carluke I, Joseph J, Rai A, Reed M, Walker K; arcOGEN Consortium, Doherty SA, Jonsdottir I, Maciewicz RA, Muir KR, Metspalu A, Rivadeneira F, Stefansson K, Styrkarsdottir U, Uitterlinden AG, van Meurs JB, Zhang W, Valdes AM, Doherty M, Zeggini E.
A Variant in MCF2L Is Associated with Osteoarthritis
The American Journal of Human Genetics 89, 1–5, September 9, 2011 PDF
 

Urmo Võsa, Tõnu Vooder, Raivo Kolde, Krista Fischer, Kristjan Välk, Neeme Tõnisson, Retlav Roosipuu, Jaak Vilo, Andres Metspalu and Tarmo Annilo
Identification of MiR-374a as a Prognostic Marker for Survival in Patients with Early-Stage Nonsmall Cell Lung Cancer
GENES, CHROMOSOMES & CANCER 50:812–822 (2011) PDF
 

Tõnu Vooder, Andres Metspalu
Investigating gene expression profile of non-small cell lung cancer
Cent. Eur. J. Med.
DOI: 10.2478/s11536-011-0063-8 PDF

10.05.11 Liina Küttis, Hindrek Teder, Katriin Antonov, Vidrik Teder
16.05.11 Sirli Heinsoo, Mari-Liis Reim, Kati Hiieleek, Kristi Tamming
24.05.11 Egon Urgard, Eneli Oitmaa
31.05.11 - seminar jääb ESHG konverentsi tõttu ära
07.06.11 Evelin Mihailov, Katrin Männik
14.06.11 Maris Teder-Laving, Eva Reinmaa
 
Seminarid toimuvad endiselt teisipäeviti algusega 15.00 ruumis 314, v.a. 16.05, mis Leena Peltoneni konverentsi tõttu toimub esmaspäeval kell 15.00.
  

Luo C, Urgard E, Vooder T, Metspalu A.
The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging.
Med Hypotheses. 2011 Apr 27
 

Nikopensius T, Kempa I, Ambrozaitytė L, Jagomägi T, Saag M, Matulevičienė A, Utkus A, Krjutškov K, Tammekivi V, Piekuse L, Akota I, Barkane B, Krumina A, Klovins J, Lace B, Kučinskas V, Metspalu A.
Variation in FGF1, FOXE1, and TIMP2 genes is associated with nonsyndromic cleft lip with or without cleft palate.
Birth Defects Res A Clin Mol Teratol 2011; 91(4): 218-225. PDF
 

Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proença C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esko T, Fernández-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Núñez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tönjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, Doering A, Scott J, Spector TD, Loos RJ, Boomsma DI, Mooser V, Peltonen L, Stefansson K, van Duijn CM, Vineis P, Sommer WH, Kooner JS, Spanagel R, Heberlein UA, Jarvelin MR, Elliott P.
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
Proc Natl Acad Sci U S A. 2011 Apr 6  PDF

Elizabeth K. Speliotes, Laura M. Yerges-Armstrong, Jun Wu, Ruben Hernaez, Lauren J., Kim, Cameron D. Palmer, Vilmundur Gudnason, Gudny Eiriksdottir, Melissa E. Garcia, Lenore J. Launer, Michael A. Nalls, Jeanne M. Clark, Braxton D. Mitchell, Alan R. Shuldiner, Johannah L. Butler, Marta Tomas, Udo Hoffmann, Shih-Jen Hwang, Joseph M., Massaro, Christopher J. O’Donnell, Dushyant V. Sahani, Veikko Salomaa, Eric E. Schadt, Stephen M. Schwartz, David S. Siscovick, NASH CRN, GIANT Consortium (Reedik Mägi, Tõnu Esko, Helene Alavere, Mari Nelis, Makus Perola, Mari-Liis Tammesoo, Maris Teder-Laving, Andres Metspalu), MAGIC, Investigators", Benjamin F. Voight, J. Jeffrey Carr, Mary F. Feitosa, Tamara B. Harris, Caroline S. Fox, Albert V. Smith, W. H. Linda Kao, Joel N. Hirschhorn, Ingrid B. Borecki., GOLD Consortium"
Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits
PLoS Genetics, March 2011, Volume 7,  Issue 3, e1001324 PDF
  

Kristjan Välk, Tõnu Vooder, Raivo Kolde, Mari-Ann Reintam, Cathleen Petzold, Jaak Vilo, Andres Metspalu
Gene Expression Profiles of Non-Small Cell Lung Cancer: Survival Prediction and New Biomarkers
Oncology 2010;79:283–292 PDF

Palju õnne Tõnu Eskole, kes osutus valituks, et osaleda Lindau Konverentsil, kus kohtuvad üle maailma 500 andekat noorteadlast ja Nobeli preemia laureaadid.

Kord aastas ootab looduskaunis Lindau linnake (Saksamaal) paarikümmet Nobeli preemia laureaati ja 500 andekat noorteadlast üle kogu maailma. Neile noortele inimestele avaneb ainulaadne võimalus kuulata nobelistide loenguid ja suhelda maailma tippteadlaste koorekihiga vahetult.

Järgmine konverents peetakse 26.06.-01.07.2011, oodatakse kraadiõppureid ja teadureid meditsiini ja füsioloogia erialalt. Eestis omab õigust Lindau kohtumistest osavõtuks kandidaate nimetada Eesti Teaduste Akadeemial. Lindau Konverentside Nõukogu hindamiskomisjon teeb lõpliku valiku (tavaline konkurents 1:4).
  

Scheler O, Kaplinski L, Glynn B, Palta P, Parkel S, Toome K, Maher M, Barry T, Remm M, Kurg A. (2011)
Detection of NASBA amplified bacterial tmRNA molecules on SLICSel designed microarray probes.
BMC Biotechnol. 2011 Feb 28;11(1):17. PDF
 
Koumbaris G, Hatzisevastou-Loukidou H, Alexandrou A, Ioannides M, Christodoulou C, Fitzgerald T, Rajan D, Clayton S, Kitsiou-Tzeli S, Vermeesch JR, Skordis N, Antoniou P, Kurg A, Georgiou I, Carter NP, Patsalis PC.  FoSTeS, MMBIR and NAHR at the human proximal Xp region and the mechanisms of human Xq isochromosome formation
Hum Mol Genet. 2011 Feb 24. PDF

Fluoride-Cleavable, Fluorescently Labelled Reversible Terminators:
Synthesis and Use in Primer Extension

Diana C. Knapp, Saulius Serva, Jennifer D’Onofrio, Angelika Keller, Arvydas Lubys, Ants Kurg, Maido Remm and Joachim W. Engels*

Chem. Eur. J. 2011,  Feb 3. doi: 10.1002/chem.201001952. [Epub ahead of print] PDF
  

Dora 6 meetme (doktorantide õpirände) stipendium

Riin Tamm õpinguteks ja teaduskoostööks perioodil 29.01-31.03.2011  Ljubljana Ülikoolis, Sloveenias

ja Ott Scheler õpinguteks ja teaduskoostööks perioodil 21.02.2011-21.06.2011 USA ülikoolis University of Illinois
 
  

Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways.
 
Muiños-Gimeno M, Espinosa-Parrilla Y, Guidi M, Kagerbauer B, Sipilä T, Maron E, Pettai K, Kananen L, Navinés R, Martín-Santos R, Gratacòs M, Metspalu A, Hovatta I, Estivill X.
Biol Psychiatry. 2010 Dec 16.
 

04.01.11 Markus Perola
11.01.11 Andres Metspalu
18.01.11 Kaarel Krjutškov
25.01.11 Evelin Mihailov
01.02.11 Egon Urgard
08.02.11 Eneli Oitmaa
15.02.11 Tarmo Annilo
22.02.11 Tõnu Esko
01.03.11 Maris Teder-Laving
08.03.11 Katrin Männik
15.03.11 Eva Reinmaa
22.03.11 Tõnu Vooder
29.03.11 Marina Solovjova
05.04.11 Andres Kutsar, Kristo Kuus
10.05.11 Liina Küttis, Hindrek Teder, Katriin Antonov, Vidrik Teder
17.05.11 Sirli Heinsoo, Mari-Liis Reim, Kati Hiieleek, Kristi Tamming
 

Ettekannete keeleks on inglise keel. Palume esinejal saata oma ettekande teema nii biotech@ebc.ee  kui egv@geenivaramu.ee listi hiljemalt eelmisel päeval.
  

Panoutsopoulou K, Southam L, Elliott KS, Wrayner N, Zhai G, Beazley C, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Doherty M, McCaskie A, Ollier WE, Ralston SH, Spector TD, Valdes AM, Wallis GA, Wilkinson JM, Arden E, Battley K, Blackburn H, Blanco FJ, Bumpstead S, Cupples LA, Day-Williams AG, Dixon K, Doherty SA, Esko T, Evangelou E, Felson D, Gomez-Reino JJ, Gonzalez A, Gordon A, Gwilliam R, Halldorsson BV, Hauksson VB, Hofman A, Hunt SE, Ioannidis JP, Ingvarsson T, Jonsdottir I, Jonsson H, Keen R, Kerkhof HJ, Kloppenburg MG, Koller N, Lakenberg N, Lane NE, Lee AT, Metspalu A, Meulenbelt I, Nevitt MC, O'Neill F, Parimi N, Potter SC, Rego-Perez I, Riancho JA, Sherburn K, Slagboom PE, Stefansson K, Styrkarsdottir U, Sumillera M, Swift D, Thorsteinsdottir U, Tsezou A, Uitterlinden AG, van Meurs JB, Watkins B, Wheeler M, Mitchell S, Zhu Y, Zmuda JM; arcOGEN Consortium, Zeggini E, Loughlin J.

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study.
Ann Rheum Dis. 2010 Dec 21.
 

Meta-analysis of genome-wide association studies for personality
MHM de Moor, PT Costa, A Terracciano, RF Krueger, EJC de Geus, T Toshiko, BWJH Penninx, T Esko, PAF Madden, J Derringer, N Amin, G Willemsen, J-J Hottenga, MA Distel, M Uda, S Sanna, P Spinhoven, CA Hartman, P Sullivan, A Realo, J Allik, AC Heath, ML Pergadia, A Agrawal, P Lin, R Grucza, T Nutile, M Ciullo, D Rujescu, I Giegling, B Konte, E Widen, DL Cousminer, JG Eriksson, A Palotie, L Peltonen, M Luciano, A Tenesa, G Davies, LM Lopez, NK Hansell, SE Medland, L Ferrucci, D Schlessinger, GW Montgomery, MJ Wright, YS Aulchenko, ACJW Janssens, BA Oostra, A Metspalu, GR Abecasis, IJ Deary, K Ra¨ikko¨nen, LJ Bierut, NG Martin, CM van Duijn and DI Boomsma,
 
Molecular Psychiatry (2010), 1–13 PDF
 

Konkursi eesmärk on väärtustada teadus- ja arendustegevust üliõpilaskonnas, stimuleerida üliõpilaste aktiivsust teadus- ja arendustegevuse alal ja avaldada tunnustust teadus- ja arendustegevuses väljapaistvaid tulemusi saavutanud üliõpilastele ja üliõpilaskollektiividele.

Doktoriõppe üliõpilaste astmes:
Bio- ja keskkonnateaduste valdkonnas:
I preemia (25000.- EEK) Kaarel Krjutškov (Tartu Ülikool), konkursitöö „Geenikiibil põhinev genotüpiseerimise meetod, APEX-2, kui paindlik lahendus DNA variatsioonide määramiseks” eest;
 
Terviseuuringute valdkonnas:
I preemia (25000.- EEK) Katrin Kepp (Tartu Ülikool), konkursitöö „Südameveresoonkonna funktsioonis osalevad geenid: uued pärilikud DNA variandid Eesti ja Tšehhi populatsioonides” eest;
 
Tänukiri juhendajale:
Andres Metspalu (Tartu Ülikool, Tartu Ülikooli Eesti Geenivaramu) Kaarel Krjutškovi konkursitöö „Geenikiibil põhinev genotüpiseerimise meetod, APEX-2, kui paindlik lahendus DNA variatsioonide määramiseks” juhendamise eest bio- ja keskkonnateaduste valdkonnas;
 
Maris Laan (Tartu Ülikool) Katrin Kepi konkursitöö „Südameveresoonkonna funktsioonis osalevad geenid: uued pärilikud DNA variandid Eesti ja Tšehhi populatsioonides” juhendamise eest terviseuuringute valdkonnas;

Lisainfo: http://www.akadeemia.ee/et/tegevus/uudised/teated/20101208023112/

Katrin Männik, Sven Parkel, Priit Palta, Olga Žilina, Helen Puusepp, Tõnu Esko, Reedik Mägi, Margit Nõukas, Andres Veidenberg, Mari Nelis, Andres Metspalu, Maido Remm, Katrin Õunap and Ants Kurg
  
A parallel SNP array study of genomic aberrations associated with mental retardation in patients and general population in Estonia
  
European Journal of Medical Genetics, accepted 4 November 2010, Available online 26 November 2010 PDF
  

Cathy E Elks, ... Tõnu Esko, Helen Alavere, Mari Nelis, Mari-Liis Tammesoo, Andres Metspalu,  et al

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

Nature Genetics Volume: 42, Pages: 1077–1085 Year published: (2010) DOI: doi:10.1038/ng.714 Received 10 May 2010 Accepted 19 October 2010 Published online 21 November 2010 PDF

30.11 - Alenka Smid, University of Ljubljana
07.12 - Anu Tammiste, University of Tartu
14.12 - Kaarel Krjutškov, University of Tartu
 

1. Elizabeth K Speliotes, ... Tõnu Esko, Helene Alavere, Mari Nelis, Mari-Liis Tammesoo, Maris Teder-Laving, Andres Metspalu, et al.
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Nature Genetics, published online 10 October 2010; doi:10.1038/ng.686 PDF

2.Iris M Heid, .... Tõnu Esko, Mari-Liis Tammesoo, Helene Alavere, Mari Nelis, Maris Teder-Laving, Andres Metspalu, et al
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Nature Genetics, published online 10 October 2010; doi:10.1038/ng.685 PDF