24.02.14 Seda veebi enam edasi ei täiendata!

Vt. värskemat infot www.biobank.ee.

 

05.06.13 Ilmus artikkel:

Nikopensius T, Annilo T, Jagomägi T, Gilissen C, Kals M, Krjutskov K, Mägi R, Eelmets M, Gerst-Talas U, Remm M, Saag M, Hoischen A, Metspalu A. Non-syndromic tooth agenesis associated with a nonsense mutation in Ectodysplasin-A (EDA). J Dent Res 2013; 92(6): 507-511.PDF

   

15.03.13 Eesti Biokeskuse biotehnoloogia labor kuulutab välja  uurimis-stipendiumi konkursi Eesti Biokeskuse tuumiklaboris statistiliste meetodite õpinguteks 6 kuuks.

Stipendiumi taotlemiseks palume esitada hiljemalt 31.03.13 taotlus koos CV-ga. Stipendiumikomisjon teeb otsuse 1. aprillil 2013.

Taotlus esitada e-maili aadressile merike.leego@ut.ee või postiaadressile; Riia 23b, Tartu 51010. 

Finantsallikas: EU grantide overhead. 

  

06.02.13 Seminars in spring 2013

6.02 – Journal Club: Maris Alver

7.02 – BIG SEMINAR: evolution dept.

14.02 – Lab Seminar: Egon Urgard

20.02 – Journal Club: Martin Sauk

21.02 – Lab Seminar: Liis Leitsalu

6.03 – Journal Club: Urmo Võsa

7.03 – BIG SEMINAR: bioinformatics dept.

14.03 – Lab Seminar: Kaie Lokk

20.03 – Journal Club: Margit Nõukas

21.03 – Lab Seminar: Maris Teder-Laving

3.04 – Journal Club: Kristi Pettai

4.04 – BIG SEMINAR: biotechnology dept.

11.04 – Lab Seminar: Maris Alver

17.04 – Journal Club: Natalia Tšernikova

18.04 – Lab Seminar: Olga Tšuiko

2.05 – BIG SEMINAR: evolution dept.

9.05 – Lab Seminar: Marina Koltšina

15.05 – Journal Club: Aune Ahman

16.05 – Lab Seminar: Evelin Mihailov

23.05 – Students’ thesis defence

30.05 – Students’ thesis defence

6.06 – BIG SEMINAR: bioinformatics dept.

Big Seminars
TIME: 10.15 am, Thursday
LOCATION: Room 105c
Lab Seminars
TIME: 10.15 am, Thursday
LOCATION: 6th floor Room
Journal Clubs
TIME: 16.00, Wednesday
LOCATION: 6th floor Room

  

05.02.13 Ilmusid uued publikatsioonid:

1. Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, Köttgen A. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. 
Hum Mol Genet 2012; 21(24): 5329-5343., PDF

2. DNA methylation dynamics in the hepatic CYP3A4 gene promoter.
Kacevska M, Ivanov M, Wyss A, Kasela S, Milani L, Rane A, Ingelman-Sundberg M.
Biochimie. 2012 Nov;94(11):2338-44. doi: 10.1016/j.biochi.2012.07.013. Epub 2012 Jul 31. PDF
  

23.01.13 Ilmus uus publikatsioon:

In-solution hybrid capture of bisulfite-converted DNA for targeted bisulfite sequencing of 174 ADME genes
Ivanov M, Kals M, Kacevska M, Metspalu A, Ingelman-Sundberg M, Milani L.
Nucleic Acids Res. 2013, 1-9 Jan 15, PDF
  

05.01.13 Palju õnne Ott Schelerile, kes pälvis oma doktoritöö "The application of tmRNA as marker molecule in bacterial diagnostics using microarray and biosensor technology" eest Kaitseministeeriumi poolt korraldatud 2012 a. kaitsealaste magistri- ja doktoritööde avalikul konkursil III preemia.
  
04.01.13 Palju õnne meie tudengitele:

Mari-Liis Reimile, kes sai DoRa stipendiumi, et minna oma magistritöö katseid tegema Linköpingi Ülikooli, Rootsi ning 

Natalia Tšernikovale, kes sai DoRa T6 stipendiumi õpinguteks Helsingi Ülikoolis.
  

27.12.12

Ilmusid publikatsioonid:

1. Esko T, Mezzavilla M, Nelis M, Borel C, Debniak T, Jakkula E, Julia A, Karachanak S, Khrunin A, Kisfali P, Krulisova V, Aušrelé Kučinskiené Z, Rehnström K, Traglia M, Nikitina-Zake L, Zimprich F, Antonarakis SE, Estivill X, Glavač D, Gut I, Klovins J, Krawczak M, Kučinskas V, Lathrop M, Macek M, Marsal S, Meitinger T, Melegh B, Limborska S, Lubinski J, Paolotie A, Schreiber S, Toncheva D, Toniolo D, Wichmann HE, Zimprich A, Metspalu M, Gasparini P, Metspalu A, D'Adamo P.
Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity.
Eur J Hum Genet
. 2012 Dec 19. doi: 10.1038/ejhg.2012.229. PDF

2.
Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Leach IM, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Polašek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C.
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Nat Genet. 2012 Dec 23. doi: 10.1038/ng.2500. PDF

3. Uusküla L, Männik J, Rull K, Minajeva A, Kõks S, Vaas P, Teesalu P, Reimand J, Laan M (2012) Mid-gestational gene expression profile in placenta and link to pregnancy complications. PLoS One 7(11):e49248
 
PDF


4. M. Grigorova, M. Punab, O. Poolamets, S. Sõber, V. Vihljajev, B. Žilaitienė, J. Erenpreiss, V. Matulevičius, I. Tsarev, M. Laan. Study in 1790 Baltic men: FSHR Asn680Ser polymorphism affects total testes volume. Andrology, in press. Article first published online: 29 NOV 2012 DOI: 10.1111/j.2047-2927.2012.00028.x

5. Võsa U, Vooder T, Kolde R, Vilo J, Metspalu A, Annilo T.
Meta-analysis of microrna expression in lung cancer.
Int J Cancer. 2012 Dec 6.
doi:10.1002/ijc.27981. [Epub ahead of print] PubMed PMID: 23225545. PDF
  

18.12.12 Õnnitleme Tõnu Eskot, kes sai 2012. aasta üliõpilaste teadustööde riiklikul konkursil Bio- ja keskonnateaduste valdkonnas doktoriõppe üliõpilaste astmes 1. preemia. Õnnitleme ka Andres Metspalu, kes pälvis tema juhendajana haridus- ja teadusministeeriumi tänukirja!

Õnnitlused ka Katrin Männikule, kes pälvis oma doktoritöö eest
Terviseuuringute valdkonnas tänukirja!
 

16.12.12 Ilmusid publikatsioonid:

1. van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, Al-Hussani A, Asselbergs FW, Ciullo M, Danjou F, Dina C, Esko T, Evans DM, Franke L, Gögele M, Hartiala J, Hersch M, Holm H, Hottenga JJ, Kanoni S, Kleber ME, Lagou V, Langenberg C, Lopez LM, Lyytikäinen LP, Melander O, Murgia F, Nolte IM, O'Reilly PF, Padmanabhan S, Parsa A, Pirastu N, Porcu E, Portas L, Prokopenko I, Ried JS, Shin SY, Tang CS, Teumer A, Traglia M, Ulivi S, Westra HJ, Yang J, Hua Zhao J, Anni F, Abdellaoui A, Attwood A, Balkau B, Bandinelli S, Bastardot F, Benyamin B, Boehm BO, Cookson WO, Das D, de Bakker PI, de Boer RA, de Geus EJ, de Moor MH, Dimitriou M, Domingues FS, Döring A, Engström G, Ingi Eyjolfsson G, Ferrucci L, Fischer K, Galanello R, Garner SF, Genser B, Gibson QD, Girotto G, Fannar Gudbjartsson D, Harris SE, Hartikainen AL, Hastie CE, Hedblad B, Illig T, Jolley J, Kähönen M, Kema IP, Kemp JP, Liang L, Lloyd-Jones H, Loos RJ, Meacham S, Medland SE, Meisinger C, Memari Y, Mihailov E, Miller K, Moffatt MF, Nauck M, Novatchkova M, Nutile T, Olafsson I, Onundarson PT, Parracciani D, Penninx BW, Perseu L, Piga A, Pistis G, Pouta A, Puc U, Raitakari O, Ring SM, Robino A, Ruggiero D, Ruokonen A, Saint-Pierre A, Sala C, Salumets A, Sambrook J, Schepers H, Oliver Schmidt C, Silljé HH, Sladek R, Smit JH, Starr JM, Stephens J, Sulem P, Tanaka T, Thorsteinsdottir U, Tragante V, van Gilst WH, Joost van Pelt L, van Veldhuisen DJ, Völker U, Whitfield JB, Willemsen G, Winkelmann BR, Wirnsberger G, Algra A, Cucca F, d'Adamo AP, Danesh J, Deary IJ, Dominiczak AF, Elliott P, Fortina P, Froguel P, Gasparini P, Greinacher A, Hazen SL, Jarvelin MR, Tee Khaw K, Lehtimäki T, Maerz W, Martin NG, Metspalu A, Mitchell BD, Montgomery GW, Moore C, Navis G, Pirastu M, Pramstaller PP, Ramirez-Solis R, Schadt E, Scott J, Shuldiner AR, Davey Smith G, Gustav Smith J, Snieder H, Sorice R, Spector TD, Stefansson K, Stumvoll M, Wilson Tang WH, Toniolo D, Tönjes A, Visscher PM, Vollenweider P, Wareham NJ, Wolffenbuttel BH, Boomsma DI, Beckmann JS, Dedoussis GV, Deloukas P, Ferreira MA, Sanna S, Uda M, Hicks AA, Martin Penninger J, Gieger C, Kooner JS, Ouwehand WH, Soranzo N, Chambers JC.
Seventy-five genetic loci influencing the human red blood cell.
2012 Dec 5. doi: 10.1038/nature11677. [Epub ahead of print] PDF

2. Amin N, Hottenga JJ, Hansell NK, Janssens AC, de Moor MH, Madden PA, Zorkoltseva IV, Penninx BW, Terracciano A, Uda M, Tanaka T, Esko T, Realo A, Ferrucci L, Luciano M, Davies G, Metspalu A, Abecasis GR, Deary IJ, Raikkonen K, Bierut LJ, Costa PT, Saviouk V, Zhu G, Kirichenko AV, Isaacs A, Aulchenko YS, Willemsen G, Heath AC, Pergadia ML, Medland SE, Axenovich TI, de Geus E, Montgomery GW, Wright MJ, Oostra BA, Martin NG, Boomsma DI, van Duijn CM.
Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions
2012 Dec 5. doi: 10.1038/ejhg.2012.263. [Epub ahead of print], PDF

3. The CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA, Stirrups K, König IR, Cazier JB, Johansson A, Hall AS, Lee JY, Willer CJ, Chambers JC, Esko T, Folkersen L, Goel A, Grundberg E, Havulinna AS, Ho WK, Hopewell JC, Eriksson N, Kleber ME, Kristiansson K, Lundmark P, Lyytikäinen LP, Rafelt S, Shungin D, Strawbridge RJ, Thorleifsson G, Tikkanen E, Van Zuydam N, Voight BF, Waite LL, Zhang W, Ziegler A, Absher D, Altshuler D, Balmforth AJ, Barroso I, Braund PS, Burgdorf C, Claudi-Boehm S, Cox D, Dimitriou M, Do R; DIAGRAM Consortium; CARDIOGENICS Consortium, Doney AS, Mokhtari NE, Eriksson P, Fischer K, Fontanillas P, Franco-Cereceda A, Gigante B, Groop L, Gustafsson S, Hager J, Hallmans G, Han BG, Hunt SE, Kang HM, Illig T, Kessler T, Knowles JW, Kolovou G, Kuusisto J, Langenberg C, Langford C, Leander K, Lokki ML, Lundmark A, McCarthy MI, Meisinger C, Melander O, Mihailov E, Maouche S, Morris AD, Müller-Nurasyid M; MuTHER Consortium, Nikus K, Peden JF, Rayner NW, Rasheed A, Rosinger S, Rubin D, Rumpf MP, Schäfer A, Sivananthan M, Song C, Stewart AF, Tan ST, Thorgeirsson G, Schoot CE, Wagner PJ; Wellcome Trust Case Control Consortium, Wells GA, Wild PS, Yang TP, Amouyel P, Arveiler D, Basart H, Boehnke M, Boerwinkle E, Brambilla P, Cambien F, Cupples AL, de Faire U, Dehghan A, Diemert P, Epstein SE, Evans A, Ferrario MM, Ferrières J, Gauguier D, Go AS, Goodall AH, Gudnason V, Hazen SL, Holm H, Iribarren C, Jang Y, Kähönen M, Kee F, Kim HS, Klopp N, Koenig W, Kratzer W, Kuulasmaa K, Laakso M, Laaksonen R, Lee JY, Lind L, Ouwehand WH, Parish S, Park JE, Pedersen NL, Peters A, Quertermous T, Rader DJ, Salomaa V, Schadt E, Shah SH, Sinisalo J, Stark K, Stefansson K, Trégouët DA, Virtamo J, Wallentin L, Wareham N, Zimmermann ME, Nieminen MS, Hengstenberg C, Sandhu MS, Pastinen T, Syvänen AC, Hovingh GK, Dedoussis G, Franks PW, Lehtimäki T, Metspalu A, Zalloua PA, Siegbahn A, Schreiber S, Ripatti S, Blankenberg SS, Perola M, Clarke R, Boehm BO, O'Donnell C, Reilly MP, März W, Collins R, Kathiresan S, Hamsten A, Kooner JS, Thorsteinsdottir U, Danesh J, Palmer CN, Roberts R, Watkins H, Schunkert H, Samani NJ.
Large-scale association analysis identifies new risk loci for coronary artery disease
Nat Genet. 2012 Dec 2. doi: 10.1038/ng.2480. [Epub ahead of print] PDF
 

28.11.12 Ilmusid publikatsioonid:

Urmo Võsa, Tõnu Vooder, Raivo Kolde, Jaak Vilo, Andres Metspalu, Tarmo Annilo
Meta-analysis of microRNA expression in lung cancer
International Journal of Cancer

Tsoi L. C. et al ... T. Esko, A. Metspalu,
Identification of 15 new proriasis susceptibility loci highlights the role of innate immunity.
Nat. Gen. 2012 Nov 11, doi: 10.1038/ng.3467 PDF

 

22.11.12 Palju õnne meie teadurile, Riin Tammele, kes pälvis 16. novembril toimunud teadusmeedia konverentsil "Teadushimuline meedia" teaduse populariseerimise auhinna. Riin Tammele omistati II preemia kategoorias "Parim teadust ja tehnoloogiat populariseeriv teadlane, ajakirjanik, õpetaja vms." teadusaasta saadikuna peetud ettekannete eest Eesti koolides.
 
13.10.12 Andsime sisse USA ja Euroopa patenditaotluse:

Leiutajad: Anu Tammiste, Lili Milani, Krista Fischer, Tõnu Esko, Kristi Pettai, Kaarel Krjutškov, Reedik Mägi, Merike Leego, Eduard Maron, Andres Metspalu
Title: "A method and a Kit to Predict Response to Antidepressant Treatment"
USA taotluse nr.: US13/648010, sisse antud 09.10.12
EPO taotluse nr.: EP12188273.2, sisse antud 12.10.12
Prioriteedikuupäev: 13.10.2011, prioriteeditaotlus US61/546607 (US provisional)
  

09.10.12 Ilmusid publikatsioonid:

1. Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS; KidneyGen Consortium; CKDGen Consortium, Albrecht E; GUGC consortium (incl. R. Mägi, T. Haller, A. Metspalu, A. Salumets, T. Esko), Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T.
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
2012 Jul 15;44(8):904-9. doi: 10.1038/ng.2352. PDF

2. Henrik Dobewall, Anu Realo, Jüri Allik, Tõnu Esko, Andres Metspalu
Self-Other Agreement in Happiness and Life-Satisfaction: The role of Personality Traits
Social Indicators Research, ISSN 0303-8300, Published on-line 27 September 2012
 

18.09.12 Reedel, 19. oktoobril 2012. aastal kell 16.15 kaitseb Tõnu Esko Tartu Ülikooli Molekulaar- ja rakubioloogia Instituudis (Riia 23B, Eesti Biokeskuse auditoorium, ruum nr. 105) doktoritööd “Novel applications of SNP array data in the analysis of the genetic structure of Europeans and in genetic association studies” (“Genotüpiseerimiskiibi andmete uudsed rakendused Euroopa geneetilise struktuuri analüüsil ning geneetilistes assotsiatsioonuuringutes”) geenitehnoloogia erialal.
Juhendaja: TÜ MRI professor Andres Metspalu.
Oponent: Professor Tiina Paunio, Helsinki Ülikool, Soome Vabariik
 
13.09.12 Katrin Männiku PhD kraadi kaitsmine
 
Reedel, 14. septembril kaitseb Katrin Männik eksternina doktoritööd "Exploring the genomics of cognitive impairment: whole-genome SNP genotyping experience in Estonian patients and general population" ("Intellektipuude genoomsed põhjused: kogu-genoomi SNP genotüpiseerimisanalüüs Eesti patsientidel ja üldpopulatsioonis") geenitehnoloogia erialal.

Juhendaja: TÜ MRI professor Ants Kurg.

Oponent: Doktor Reinhard Ullmann, Inimese Molekulaargeneetika Osakond, Max Planck'i nimeline Molekulaargeneetika Instituut, Berliin, Saksamaa Liitvabariik
 

13.09.12

Ilmunud on publikatsioonid:

1. E. Preiksaitiene, K. Männik, V. Dirse, A. Utkus, Z. Ciuladaite, J. Kasnauskiene, A. Kurg, V. Kucinskas
A novel de novo 1.8 Mb microdeletion of 17q21.33 associated with intellectual
disability and dysmorphic features
Eur J Med Genet. 2012 Jul 27. [Epub ahead of print], PDF

2. Beate Beer Kaarel Krjutškov Robert Erb Triin Viltrop and Herbert Oberacher
A novel amplification strategy for genotyping with liquid chromatography-electrospray ionization mass spectrometry
Analyst, 2012, PDF

 

12.09.12 Meie õppetool hakkab sellest aastast lugema sügissemestril uut ainet:
Üle-genoomsed tehnoloogiad molekulaarbioloogias, 3AP, LOMR.01.006

Vt. lisainformatsiooni.
 
11.09.12 Ilmunud on publikatsioonid:

1. Vesna Boraska, ... T. Esko, K. Fischer, E. Mihailov, A. Metspalu, M. Perola, etc.
Genome-wide meta-analysis of common variant differences between men and women
Human Molecular Genetics, 2012 1–11, PDF

2. arcOGEN Consortium and arcOGEN Collaborators.
Identifi cation of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study
Lancet. 2012 Sep 1;380(9844):815-23. Epub 2012 Jul 3.: http://dx.doi.org/10.1016/S0140-6736(12)60681-3, PDF

3. Ruth McQuillan, ... T. Esko, Mart Kals, Lili Milani, Krista Fischer, Andres Metspalu, Markus Perola, etc.
Evidence of Inbreeding Depression on Human Height
PLOS Genetics, July 2012, Volume 8, Issue 7, PDF

4. Scott RA, Lagou V, Welch RP, ... Esko T, A. Metspalu, et al.
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Nature Genetics, published online 12 August 2012; doi:10.1038/ng.2385, PDF

5. MorrisAP, Voight BF, Teslovich TM, ...Esko T, A. Metspalu, et al.
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Nature Genetics, published online 12 August 2012; doi:10.1038/ng.2383, PDF
 
 

08.09.12

Sügisseminarid 2012/Autumn seminars 2012

AEG: kell 10.15, neljapäev/TIME: at 10.15 am, Thursday;
KOHT: ruum 105c, Riia 23b
/LOCATION: Room 105c, Riia 23b;

6. september –Tõnu Esko
13. september – Katrin Männik
20. september - Tiit Nikopensius

27.september – Teadlaste ÖÖ
4.oktoober -
Kaie Lokk, Mart Kals
11.oktoober – Tom Haller
18. oktoober –
EstSHG konverents
25.oktoober - Lili Milani
1. november - UrmoVõsa
8. november - Margit Nõukas
15. november–Natasha Strydom
22. november – Riin Tamm
29. november -
Eva Reinmaa
6. detsember - Anu Tammiste
13. detsember - Aune Ahman

 

01.07.12 Ilmusid publikatsioonid:


1. Kaie Lokk, Tõnu Vooder, Raivo Kolde, Kristjan Välk, Urmo Võsa, Retlav Roosipuu, Lili Milani, Krista Fischer, Marina Koltsina, Egon Urgard, Tarmo Annilo, Andres Metspalu, Neeme Tõnisson
Methylation Markers of Early-Stage Non-Small Cell Lung Cancer
PLOS One, June 2012, Vol 7, Issue 6, PDF

2. Verhoeven VJ, Hysi PG, Saw SM, Vitart V, Mirshahi A, Guggenheim JA, Cotch MF, Yamashiro K, Baird PN, Mackey DA, Wojciechowski R, Ikram MK, Hewitt AW, Duggal P, Janmahasatian S, Khor CC, Fan Q, Zhou X, Young TL, Tai ES, Goh LK, Li YJ, Aung T, Vithana E, Teo YY, Tay W, Sim X, Rudan I, Hayward C, Wright AF, Polasek O, Campbell H, Wilson JF, Fleck BW, Nakata I, Yoshimura N, Yamada R, Matsuda F, Ohno-Matsui K, Nag A, McMahon G, Pourcain BS, Lu Y, Rahi JS, Cumberland PM, Bhattacharya S, Simpson CL, Atwood LD, Li X, Raffel LJ, Murgia F, Portas L, Despriet DD, van Koolwijk LM, Wolfram C, Lackner KJ, Tönjes A, Mägi R, Lehtimäki T, Kähönen M, Esko T, Metspalu A, Rantanen T, Pärssinen O, Klein BE, Meitinger T, Spector TD, Oostra BA, Smith AV, de Jong PT, Hofman A, Amin N, Karssen LC, Rivadeneira F, Vingerling JR, Eiríksdóttir G, Gudnason V, Döring A, Bettecken T, Uitterlinden AG, Williams C, Zeller T, Castagné R, Oexle K, van Duijn CM, Iyengar SK, Mitchell P, Wang JJ, Höhn R, Pfeiffer N, Bailey-Wilson JE, Stambolian D, Wong TY, Hammond CJ, Klaver CC.
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium
2012 Jun 5., PDF

3. Kazma R, Babron MC, Gaborieau V, Génin E, Brennan P, Hung RJ, McLaughlin JR, Krokan HE, Elvestad MB, Skorpen F, Anderssen E, Vooder T, Välk K, Metspalu A, Field JK, Lathrop M, Sarasin A, Benhamou S; ILCCO consortium.
Lung cancer and DNA repair genes: multilevel association analysis from
the International Lung Cancer Consortium
Carcinogenesis. 2012 May;33(5):1059-64. Epub 2012 Mar 1., PDF

4. Ellinghaus E, Stuart PE, Ellinghaus D, Nair RP, Debrus S, Raelson JV, Belouchi M, Tejasvi T, Li Y, Tsoi LC, Onken AT, Esko T, Metspalu A, Rahman P, Gladman DD, Bowcock AM, Helms C, Krueger GG, Koks S, Kingo K, Gieger C, Wichmann HE, Mrowietz U, Weidinger S, Schreiber S, Abecasis GR, Elder JT, Weichenthal M, Franke A.
Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL.
2012 Apr;132(4):1133-40. doi: 10.1038/jid.2011.415. Epub 2011 Dec 15., PDF

 

16.05.12 Ilmus uus publikatsioon:

Josine L. Min, George Nicholson, Ingileif Halgrimsdottir, Kristian Almstrup, Andreas Petri, Amy Barrett, Mary Travers, Nigel W. Rayner, Reedik Mägi, Fredrik H. Pettersson, John Broxholme, Matt J. Neville, Quin F. Wills, Jane Cheeseman, The GIANT Consortium", The MolPAGE Consortium", Maxine Allen, Chris C. Holmes, Tim D. Spector, Jan Fleckner, Mark I. McCarthy, Fredrik Karpe, Cecilia M. Lindgren, Krina T. Zondervan

Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes
PLoS Genetics, February 2012 | Volume 8 | Issue 2, PDF
 

16.05.12 18. mail kell 10.00 esinevad laboriseminaril meile:

Maris Alver
Jürgen Pahla
Kadi Rosenthal
Kristi-Liina Arusoo
Kristine Kreitsman

Seminar toimub ruumis Riia-23, 218.
 
20.04.12 Osa biotehnoloogia õppetoolist kolib aprilli lõpus - mai algul uude majja aadressil Riia 23B. Prof. Andres Metspalu on edaspidi kättesaadav uue maja ruumist 426. Telefoni numbrid jäävad samaks, uus faxi number on 7374060.
 
 
 
   

 






 


   



 

  

 

 

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